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Module 12 Kawasaki Disease
Terms in this set (13)
Kawasaki disease essential of diagnosis:
-Fever, conjunctivitis, oral mucosal changes, rash, cervical lymphadenopathy, peripheral extremity changes
-Elevated ESR and CRP
What is Kawasaki Disease?
multisystemic acute vasculitis that primarily affects young children, particularly of Asian ancestry.
Arteritis affecting large to medium-sized and small vessels.
The leading cause of acquired heart disease in children. It is thought to be triggered by an infectious agent. S/s are fever, conjunctival hyperemia, cervical lymphadenopathy, cracking skin, and coronary artery aneurysms.
Fever for 5 or more days (unresponsive to antibiotics), Bilateral conjunctivitis without exudation, Erythema of oral mucosa (strawberry tongue), Changes in the extremities, such as peripheral edema and erythema with desquamation of palms and soles, Polymorphous rash, Cervical lymphadenopathy are all clinical manifestations for what disease?
Kawasaki Disease Skin Changes
A clinical diagnosis of "complete" Kawasaki disease requires, in the absence of other processes, explaining the current illness of fever and 4 of WHAT CRITERIA for at least 5 days?
-bilateral nonexudative conjunctivitis
-mucous membrane changes of at least one type
-----erythema, swelling, fissuring of lips
-peripheral extremity changes of at least one type
-----erythema of palms and soles
-----induration of the hands and feet
-----Beau lines (transverse grooves of nails)
-cervical lymphadenopathy >1.5cm
*****An "incomplete" form is diagnosed when only 2 criteria are met
The classic syndrome is often preceded by?
Nonspecific symptoms including irritability, vomiting, anorexia, cough, and diarrhea for up to 10 days.
Major complications of Kawasaki Disease are:
3Cs- Cardiotoxicity, Convulsions, Coma
Treatment and prevention of Kawasaki Disease:
-IVIG given within first 10 days of illness or for those presenting later with persistent fever etc.
-Routine childhood vaccinations (delay live vaccines)
-TNF blockers for refractory cases
-Anticoagulants in patients with aneurysms >8mm
-Thrombolytics for MI
When to refer patient with Kawasaki disease:
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