Antacids (Aluminum hydroxide, Magnesium hydroxide, Calcium carbonate)
NOTE: Affect absorption, bioavailability, or urinary excretion of other drugs by altering gastric and urinary pH or by delaying gastric emptying.
Tox: Aluminum hydroxide: constipation and hypophosphatemia; proximal muscle weakness, osteodystrophy, seizures.
Magnesium hydroxide: diarrhea, hyporeflexia, hypotension, cardiac arrest.
Calcium carbonate: hypercalcemia, rebound acid increases.
All can cause hypokalemia.