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Terms in this set (19)
Watching the stem cells develop into the many different types of cells, such as bone, heart, and nerve / tissue cells, can provide information on how disease and other conditions develop
Stem cells can develop into other stem cells, making them possibly self-renewing
Stem cells have been identified within amniotic fluid, which is found in the sac that surrounds the developing fetus
Scientists have genetically reprogrammed adult stem cells to act like embryonic stem cells, these cells are called induced pluripotent stem cells
In Vitro Fertilization is a process where an egg cell is fertilized in a lab and then implanted in the uterus, usually for women who can not get pregnant on their own
Stem cells are taken from this process
The average process of IVF takes about 2 weeks
For stem cells to be useful, they must:
"Proliferate extensively and generate sufficient quantities of cells for making tissue.
Differentiate into the desired cell type(s).
Survive in the recipient after transplant.
Integrate into the surrounding tissue after transplant.
Function appropriately for the duration of the recipient's life.
Avoid harming the recipient in any way."
One goal for scientists is to understand how undifferentiated cells become differentiated cells
Testing on mice has lead researchers to find that transplanting bone marrow stromal cells into a damaged heart can have beneficial effects
One great possibility for stem cells is the potential for cell-based therapies
One method of cell therapy is a bone marrow transplant, which is used for treating many blood disorders
"After the bone marrow cells from the matched donor are infused, the self-renewing stem cells find their way to the bone marrow and begin to replicate."
Not everyone who needs a transplant has a good donor match; not everyone's transplant will be a full success if the bone marrow fails to completely repopulate
"Cell therapy treatment strategies include isolation and transfer of specific stem cell populations, administration of effector cells, induction of mature cells to become pluripotent cells, and reprogramming of mature cells."
Totipotent cells are cells that have the ability to differentiate into any kind of cell
Totipotent cells provide basic material for the development of all organs and tissues
"no approach to the differentiation of ES cells has yet yielded a 100% pure population of mature progeny"
"Two properties are generally considered to define a stem cell, the capacity for long-term self-renewal without senescence and pluripotency, the ability to differentiate into one or more specialized cell types"