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37 terms

pancreas dz

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what are the 2 functions of the pancreas
endocrine (beta cells/insulin) & exocrine (digestive enzymes amylase & lipase)
what is a congenital pancreas dz
endocrine pancreas insufficiency
what is an aquired pacreas dz
pancreatitis (canine & feline)
what is canine pancreatitis
acute/hemorrhagic
can occur at any time, often after a fatty meal
extreme adbominal pain, roaching
vomiting, maybe blood
diarrhea
lethargy
what is the pathology of canine pancreatitis
obstruction of flow of amylase/lipase
starts digesting pacreas, then leaks into abdomianl cavity, digesting surrounding tissue
life threatening
what is the dx of canine pacreatitis
history
CBC/profile
cPL is definitive dx
xray
what is cPL
pancreatic lipase immunoreactive assay
what is the treatment for canine panreatitis
supportive therapy
fluids
monitor potassium
antiemetics
pain mgmt (butorphanol)
antibiotics
what is the prognosis of canne pacreatitis
highly variable
poor if DIC
chronic dz may develop after acute episode
what are the signs of chronic caine pancreatitis
intermittant vomiting
lethargy
mabye diarrhea
rule out other causes of these symptoms
cPL imortant (elevated in chronic)
how is chrinic canine pancreatitis managed
wt loss
low fat/hi cab diet
what are the signs of feline pancreatitis
(acute or chronic)
chronic more common
abdominal pan
itermittent vomit
inappetance
rule out ther causes of symptoms
what is frequently associated with feline pancreatitis
IBD
pandora's
hepatic lipidosis
how is feline pacreatitis dx'd
index of suspicion
lab work:fPL CBC profile
xrays
how is feline pancreatitis treated
treat underlying dz
support during acute phases
feed grain free diet
antiemetics
fluids
who does pancreatic cancer affect
dogs & ferrets, rare
what is insulinoma
pancreatic cancer
how is pancreatic cancer dx'd
profoundly low blood glucose
ultrasound
how is pancreatic cancer treated
Sx
xray lungs to make sure not metastitcised
when does diabetes mellitus occur
when the endocrine function of insulin production malfunctions
what are the 2 types of diabetes mellitus and how are they different
type 1 is insulin dependent, deficiency in amt of insulin produced
type 2 is adult onset, resistence of cells to insulin
what are some causes of diabetes mellitus
heredity
autoimmune
chronic pancreatitis (beta cells get damaged)
what is the pathology of diabetes mellitus
lack of glucose entering cells causes increased blood glucose, glucosuria, perm neurological damage, muscle mass loss
ketosis
what are the clinical signs of non ketotic dibetes mellitus
dehydration
pu/pd
polyphagia
cararcts (sudden)
Uti
plantigrade stance in cats
what are teh clinical signs of ketitic diabetes mellitus
depression
weakness
tachpnea
vomiting
acetone breath odor
what dog breeds are predisposed to doabetes mellitus
schauzers
poodles
keeshonds
daschunds
cocers
beagles
cairn terriers
what cat types are predisposed to diabetes mellitus
obese
older
may occur with heptaic lipidosis
what is the dx of diabetes mellitus
clinical signs
blood glucose >200
glucosuria w/ketones
what is the treatment of diabetes mellitus
regulate blood glucose levels
insulin injections 1 or 2 times/day
what types of insulin are there
human: humalin, glargine (lantus)
vet: pork/beef NPH, PZI
how do you check insulin in cats & dogs
cats: ear prick
dogs: urine check
what types of insulin do cats & dogs get respectively
cats: PZI, lantus/glargine
dogs: NPH
what are other treatment considerations for diabetes mellitus
exercise, mod & consistent
grain free diet for cats
high fiber & wt loss diet for dogs
how is diabetes mellitus regulated
manage underlying sz conditions
consistency is key
spay/neuter b/c hormones bad for regulating glucose in blood
what is ketoacidosis
persistent hypergycemia
ketotic & acidic blood
how is ketoacidosis treated
hosptialize
fluid support
IV regular insulin
montor potassium levels
monotr BG hourly
what are other complications from diabetes mellitus
insulin shock from too much insulin or not enough food
stagger/collapse at peak insulin (6-8 hrs after injection)
coma if untreated
treat with glucose, karo or honey on gums
bring to hospital