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45 terms

Micro Bacteria

STUDY
PLAY
where in bacteria are many beta lactamases?
periplasmic space
structures unique to gram+?
teichoic acid
structures unique to gram-?
endotoxin, LPS, periplasmic space
PAS stain for what bug?
Whipple's disease
India ink for what bug?
Cryptococcus
Silver stain for what bug?
fungi, legionella
Important obligate aerobes?
Pseudomonas
M. tuberculosis (explains why it reactivates in upper lobes with high O2)
Big mama anaerobes?
Clostridium
Bacteroides
Quellung + bugs?
Some Killers Have Pretty Pretty Nice Capsules
- Salmonella
- Klebsiella
- H flu
- Pseudomonas
- Strep Pneumo
- Neisseria
- Citrobacter
Urease + bugs?
P PUNCH
- Proteus
- Pseudomonas
- Ureoplasma
- Nocardia
- Cryptococcus
- H pylori
IgA protease?
SHiN: Strep pneumo, H flu, Moraxella, Neisseria (think respiratory infx, also can take up DNA from enviro aka transformation)
Toxins encoded in a lysogenic phage?
ABCDE
- ShigA-like
- Botulinum
- Cholera
- Diphtheria
- Erythrogenic toxin of S. pyogenes
3 things you don't want to take a bath in?
VOmit, ABscess, SNot
- Viridans, Optochin resistant
- Agalactiae, Bacitracin resistant
- Saprophyticus, Novobicin resistant
ADP ribosylaters?
Pertussis (inhib Gi, increased cAMP)
Cholera (stim Gs, increased cAMP)
E coli (stim Gs, increased cAMP)
C diphtheria (inactivates EF2)
Pseudomonas (inactivates EF2)
staph aureus virulence factor?
protein A
staph aureus exotoxins?
TSST: scalded skin, toxic shock syndrome
strep pyogenes virulence factor?
protein M
strep pyogenes exotoxin?
erythrogenic (scarlet fever)
TSST (toxic shock)
Clostridia toxins?
- C. tetani (tetanospasmin, blocks glycine and GABA)
- C. botulinum (blocks ACh release)
- C. perfringens (alpha toxin, lecithinas, gas gangrene)
- C. diff (Toxin A enterotoxin in gut, Toxin B cytotoxin destroying cytoskeletal structure of enterocytes leading to pseudomembranous colitis)
what bug has actin rockets to move cell to cell?
Listeria
what's a Ghon complex?
Ghon focus (lower lobes) and lobar and perihilar LN involvement (primary infection)
when do you get cavitary upper lobe TB lesions?
secondary infection
types of leprosy?
Tuberculoid (TH1, few skin nodules)
Lepromatous (TH2, diffuse, communicable, lethal)
bacteria that can cause colon cancer?
S. bovis
Diseases caused by S. pyogenes?
LINGER
Lymphangitis
Impetigo
Necrotizing fasciitis
Glomerulonephritis
Erysipelas
Rheumatic fever
chocolate agar plus factor V and X for growth?
H flu
charcoal yeast with iron and cystein?
Legionella
bug that causes Pontiac fever?
legionella
4 As of Klebsiella?
Aspiration pneumo
Abscess in lungs
Alcoholics
diAbetes
Red currant jelly sputum for what bug?
Klebsiella
common antecedant to Guillain Barre?
Campylobacter
surfer's disease?
Leptospira interrogans
stages of syphilis?
1: painless chancre
2: disseminated w/rash, condylomata
3: gumma, aortitis, neuro
causes of VDRL false positives?
VDRL
- Viruses
- Drugs
- Rheumatic fever
- Lupus, Leprosy
Clue cells under micro?
Gardnerella vaginalis (BV)
Palm and sole rash?
- Coxsackievirus A (hand foot mouth)
- Rocky Mt spotted fever
- Syphilis
repiratory droplets?
N meningitidis
H flu
TB
cause granulomas?
TB
Leprosy
Sarcoid
Syphilis
Bartonella
Listeria
Crohns
eosinophilic pneumonia?
Loeffler's (parasite)
Aspergillus
Churg strauss
causes of meningitis in neonate?
Baby BEL
Group B strep
Ecoli
Listeria
causes of osteomyelitis?
Staph aureus
Salmonella (sicle cell)
Staph epidermidis (prosthetic joint)
Pseudomonas (diabetic foot)
ELEK test for...?
Corynebacterium toxin
gas gangrene?
C perfringens
grown on cysteine-tellurite agar as dark black, slightly iridescent colonies?
C. diphtheriae
grows on Bordet-Gengou?
Bordetella pertussis