where in bacteria are many beta lactamases?
structures unique to gram+?
structures unique to gram-?
endotoxin, LPS, periplasmic space
PAS stain for what bug?
India ink for what bug?
Silver stain for what bug?
Important obligate aerobes?
M. tuberculosis (explains why it reactivates in upper lobes with high O2)
Big mama anaerobes?
Quellung + bugs?
Some Killers Have Pretty Pretty Nice Capsules
- H flu
- Strep Pneumo
Urease + bugs?
- H pylori
SHiN: Strep pneumo, H flu, Moraxella, Neisseria (think respiratory infx, also can take up DNA from enviro aka transformation)
Toxins encoded in a lysogenic phage?
- Erythrogenic toxin of S. pyogenes
3 things you don't want to take a bath in?
VOmit, ABscess, SNot
- Viridans, Optochin resistant
- Agalactiae, Bacitracin resistant
- Saprophyticus, Novobicin resistant
Pertussis (inhib Gi, increased cAMP)
Cholera (stim Gs, increased cAMP)
E coli (stim Gs, increased cAMP)
C diphtheria (inactivates EF2)
Pseudomonas (inactivates EF2)
staph aureus virulence factor?
staph aureus exotoxins?
TSST: scalded skin, toxic shock syndrome
strep pyogenes virulence factor?
strep pyogenes exotoxin?
erythrogenic (scarlet fever)
TSST (toxic shock)
- C. tetani (tetanospasmin, blocks glycine and GABA)
- C. botulinum (blocks ACh release)
- C. perfringens (alpha toxin, lecithinas, gas gangrene)
- C. diff (Toxin A enterotoxin in gut, Toxin B cytotoxin destroying cytoskeletal structure of enterocytes leading to pseudomembranous colitis)
what bug has actin rockets to move cell to cell?
what's a Ghon complex?
Ghon focus (lower lobes) and lobar and perihilar LN involvement (primary infection)
when do you get cavitary upper lobe TB lesions?
types of leprosy?
Tuberculoid (TH1, few skin nodules)
Lepromatous (TH2, diffuse, communicable, lethal)
bacteria that can cause colon cancer?
Diseases caused by S. pyogenes?
chocolate agar plus factor V and X for growth?
charcoal yeast with iron and cystein?
bug that causes Pontiac fever?
4 As of Klebsiella?
Abscess in lungs
Red currant jelly sputum for what bug?
common antecedant to Guillain Barre?
stages of syphilis?
1: painless chancre
2: disseminated w/rash, condylomata
3: gumma, aortitis, neuro
causes of VDRL false positives?
- Rheumatic fever
- Lupus, Leprosy
Clue cells under micro?
Gardnerella vaginalis (BV)
Palm and sole rash?
- Coxsackievirus A (hand foot mouth)
- Rocky Mt spotted fever
causes of meningitis in neonate?
Group B strep
causes of osteomyelitis?
Salmonella (sicle cell)
Staph epidermidis (prosthetic joint)
Pseudomonas (diabetic foot)
ELEK test for...?
grown on cysteine-tellurite agar as dark black, slightly iridescent colonies?
grows on Bordet-Gengou?
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