blocks receptor sites, reduces, inhibits, makes things less likely to fire,slows down,(eg. depressants, barbiturates, alcohol, valium) this is what GABA does, slows body processes down
works as an agonist;opens up sodium channels, more likely to fire
blocks auto receptors, directly activates post synaptic receptors for dopamine, norepinephrine, 5HC, reduces MAO
mimics anandamide-NT,THC ingredient, lateral hypothalamus(ANS) (hunger&thirst), time distortions
NT most involved in addiction; acts at the nucleus accumbens
in the reward/reinforcement pathway, produces euphoria and repeat of drug use. helps control voluntary muscle movement
neurotransmitters bind to the receptor sites on the pre-synaptic neurons and are signaled to stop releasing
alcohol typically acts on NT- GABA receptor
blood alcohol poisoning threshold
.40 can cause death
scarring of the liver due to heavy alcohol consumption
cancer of mouth
heavy drinking can lead to this type of cancer
Alcohol during pregnancy
lead to FAS, cause mental retardation #1 reason, result in birth defects
Frontal lobe of brain
alcohol shuts down this area of the brain
1830 alcohol consumption
7.1 gallon/ Today's consumption 1.8 gallons
you are not unconscious, loss of memory of events that occur
brown-outs remember certain thins
Cirrhosis of the liver
only about 10-20% of heavy drinkers develop this disease
1-3 drinks a day is associated with reduced risk
13 million in USA
stress hormone, weight gain, increases with alcohol consumption
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