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BCMB Exam 2

Terms in this set (33)

Which energy source is used to generate ATP from ADP and Pi?
Oxidation of carbon fuels to CO2
The reduced forms of flavin adenine dinucleotide is:
FADH2
Which option ranks carbon from its most reduced to most oxidized form (left to right, respectively):
CH4, -COOH, CO2
Which of the falling is NOT an electron carrier used primarily for ATP synthesis?
NADPH IS NOT. NADH and FADH2 IS
Based on your knowledge of the free energy of oxidation (oxidation state of carbon), which is the best feel source?
Fatty Acids
The phosphoric donor in the formation of phosphoenolpyruvate is :
GTP
The enzyme involved in shuttling carbons involved in gluconeogenesis from the mitochondria to the cytosol is called:
malate dehydrogenase
Glucose 6-phosphatase is found in which cellular location?
endoplasmic reticulum
High levels of ATP and citrate:
Indicates a high-energy well fed state, promotes gluconeogenesis, and inhibits glycolysis.
Hormonal activation of cyclic AMP levels:
increases the activation of gluconeogensis
The major site for gluconeogenesis is in which of the following tissues?
the liver
The activated carrier of acyl groups is:
Coenzyme A
What are the steps involved (in order) in the conversion of pyruvate to acetyl CoA?
Decarboxylation, oxidation, transfer to CoA
Which of the following conditions will activate PDH kinase, which catalyzes the phorphorylat
Elevated concentrations of NADH and ATP and acetyl CoA
Energy is harvested from the citric acid cycle in the form of:
FADH2, NADH, ATP
Carbons ener and exit the citric acid cycle, respectively, in the form of:
Acetyl CoA and carbon dioxide
Choose the correct path taken by a pair of electrons as they travel down the electron-transport chain.
NADH to Complex I to CoQ to Complex III to Cytochrome c to Complex IV to O2 and FADH2 to Complex II to CoQ to Complex III to Cytochrome c to Complex IV to O2
Electron flow down the electron-transport chain leads to:
The transport of protons across the inner mitochondrial membrane from inside the matrix to the intermembrane space.
Which of the following does NOT pump protons?
Complex II
The proton-motive force consists of a(n):
Chemical gradient and charge gradient
What force drives the ATP-ADP translocase?
Membrane potential from electron transport
What reaction is catalyzed by ATP synthase?
ADP3- + (HPO4)2- + H+ <=> ATP4- + H2O
Reduction potential is an indicator of the:
Affinity of a chemical species for electron.
If Delta G' for a reaction is positive, then the:
Reactants will be favored
Which enzyme in the citric acid cycle catalyzes the oxidation of carbon?
NONE OF THE FOLLOWING: citrate synthase, aconitase, Succinyl CoA synthetase
Triose phosphate isomerase catalyzes the isomerization of dihydroxyacetone phosphate (DHAP) to glyceraldehyde-3-phosphate (GAP). At equilibrium, more than 90% of the trioses are found in the DHAP form. Thus, the Keq & Delta G' for this reaction should be, respectively:
Less than 1, and positive
Based on the parameters given in each choice, which reaction is most likely to be spontaneous?
one having a Keq=50
Reaction that have positive standard free energy changes can be made to occur in cells by:
Coupling them with exergonic reactions via a common intermediate, manipulating the concentrations of products and reactants, coupling them to the hydrolysis of ATP
Which enzyme(s) is/are responsible for the following reaction?
Pyruvate + CoA + NAD+ --> Acetyl CoA + NADH + H+ +CO2
Pyruvate dehydrogenase complex
In aerobic organisms, the ultimate accept of electrons is:
O2
In aerobic metabolism, the final product of oxidation of carbon containing fuels is:
CO2
This compound serves as an acyl carrier in metabolism:
Coenzyme A
What is the "energy currency" of metabolism?
ATP
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