30 terms

DIT Neuro 16. Tumors and Anesthetics

STUDY
PLAY
Brain tumors in adults in order of prevalence
"MGM Studios"

Metastasis (MCC of brain tumors in adults)
Glioblastoma multiforme
Meningioma
Schwannoma
What is the diff between adult and child brain tumors in terms of location?
Adult = supratentorial

Child = infratentorial
What are the 3 most common primary brain tumors in adults? What are the 3 most common in children?
Adult:
1. Glioblastoma multiforme
2. Meningioma
3. Schwannoma

Child:
1. Pilocytic astrocytoma
2. Medulloblastoma
3. Ependymoma
Which primary brain tumor fits the following description?

pseudopaliisading necrosis
Glioblastoma multiforme
Which primary brain tumor fits the following description?

polycythemia
Hemangioblastoma
Which primary brain tumor fits the following description?

neurofibromatosis II
Schwannoma
Which primary brain tumor fits the following description?

associated with von Hippel-Lindau syndrome
Hemangioblastoma
Which primary brain tumor fits the following description?

foamy cells, high vascularity
Hemangioblastoma
Which primary brain tumor fits the following description?

hyperprolactinemia -> galactorrhea, amenorrhea, anovulation
Pituitary adenoma
Which primary brain tumor fits the following description?

psammomma bodies
Meningioma
Which primary brain tumor fits the following description?

fried-egg appearance
Oligodendroglioma
Which primary brain tumor fits the following description?

perivascular pseudorosettes
Ependymoma
Which primary brain tumor fits the following description?

bitemporal hemianopia
Pituitary adenoma pressing on optic chiasm
Cranopharyngioma
Which primary brain tumor fits the following description?

worst prognosis of any primary brain tumor
Glioblastoma multiforme
Which primary brain tumor fits the following description?

child with hydrocephalus
Medulloblastoma
Ependymoma
Which primary brain tumor fits the following description?

Homer-Wright pseudorosettes
Medulloblastoma
Inhaled Anesthetics
"SHINE"

Sevoflurane
Halothane (hepatotoxic)
Isoflurane (brain surgery)
Nitrous Oxide (low solubility, fast induction)
Enflurane (seizures)
Which anesthetic fits the following description?

IV, associated with hallucinations and bad dreams
Ketamine
Which anesthetic fits the following description?

inhaled, SE nephrotoxic
Methoxyflurane
Which anesthetic fits the following description?

IV, most common drug used for endoscopy
Midazolam, Fentanyl
Which anesthetic fits the following description?

inhaled, SE convulsions/seizures
Enflurane
Which anesthetic fits the following description?

inhaled, SE hepatotoxic
Halothane
Which anesthetic fits the following description?

IV, used for rapid anesthesia induction and short procedures
Propofol
Which anesthetic fits the following description?

inhaled, used for rapid anesthesia
Nitric Oxide
Which anesthetic fits the following description?

IV, decreases cerebral blood flow (important in brain surgery)
Barbiturates (Thiopental)
Which anesthetic fits the following description?

IV, does not induce histamine release like morphine
Fentanyl
Which anesthetic fits the following description?

high TG content increases risk of pancreatitis with long-term use
Propofol
What is the MOA of dantrolene?
Prevents the release of Ca2+ from the sarcoplasmic reticulum by binding to the ryanodine receptor
What is the MOA of local anesthetics? Which nerve fibers are blocked first with local anesthesia?
Block Na+ channels by binding to specific receptors on the inner portion of the channel.

Small myelinated > Small unmyelinated > Large myelinated > Large unmyelinated

Pain (lose first) > temp > touch > pressure (lose last)
What drugs can be used to reverse neuromuscular blockade?
Acetylcholinesterase inhibitors (Neostigmine)