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60 terms

15. DIT day 10 Repro I

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What are the layers of the endometrium?
Stratum basalis
stratum spongiosum
stratum compactum
Which layers of the endometrium are shed during menstruation?
Stratum spongiosum
stratum compactum
When does the basal body temperature increase occur in relation to ovulation?
24 hours after ovulation when progesterone increases
What uterine pathology is a/w excess unopposed estrogen is the main risk factor?
endometrial hyperplasia or carcinoma
What uterine pathology is a/w menorrhagia with an enlarged uterus and no pelvic pain?
Leiomyoma
What uterine pathology is a/w pelvic pain that is present only during menstruation?
Endometriosis
What uterine pathology is a/w dx by endometrial biopsy in the clinic?
Endometrial hyperplasia or carcinoma
What uterine pathology is a/w definitive diagnosis and treatment by laproscopy?
Endometriosis
What uterine pathology is a/w menstruating tissue within the myometrium?
Adenomyosis
What uterine pathology is a/w malignant tumor of the uterine smooth muscle?
Leiomyosarcoma
What uterine pathology is a/w most common gynecologic malignancy?
Endometrial carcinoma
What ovarian tumor is a/w production of AFP?
Yolk Sac Tumor
What ovarian tumor is a/w estrogen secretion causing precocious puberty?
Granulosa Cell Tumor
What ovarian tumor is a/w intraperitoneal accumulation of mucinous material?
Mucinous Cystadenocarcinoma
What ovarian tumor is a/w testosterone secretion causing virilization?
Serotoli Leydig Cell Tumor
What ovarian tumor is a/w Psammoma Bodies?
Serous Cystadenocarcinoma
What ovarian tumor is a/w multiple different tissue types?
Teratoma
What ovarian tumor is a/w a lining that is fallopian-tube like epithelium?
Serous cystadenoma
What ovarian tumor is a/w ovarian tumor + ascites + pleural effusions?
Fibromas
What ovarian tumor is a/w Call-Exner bodies?
Granulosa Cell Tumor
What ovarian tumor is a/w resembling of a bladder epithelium?
Brenner Tumor
What ovarian tumor is a/w elevated beta hCG?
Dysergiminoma
Choriocarcinoma
An obese woman presents with amenorrhea and increased levels of serum testosterone; what is the dx?
Polycystic ovarian syndrome
A pt with polycystic ovarian disease is most at risk to developing what cancer?
Endometrial
Why is progesterone given in combo with estrogen replacement?
Decrease risk of endometrial cancer
A pregnant woman with a previous c-section is at increased risk for what?
Scarring can lead to a placenta previa or accreta
Pregnant woman at 16 weeks gestation presents with atypically large abdomen and HTN; what abnormality may be seen on blood test and the disorder?
beta hCG in a molar pregnancy
A 23 yo female on Rifampin for TB prophylaxis and on birth control (estrogen) gets pregnant, why?
Rifampin increases CP-450 causing an increased metabolism of estrogen leading to less effective birth control.
Best option for birth control in a mentally retarded patient?
IM Medroxyprogesterone
What is abruptio placentae?
Painful bleeding in 3rd trimester due to abrupt detachment leading to fetal death.
A/w DIC; smoking; cocaine; HTN; spousal abuse
What is Placenta accreta?
Massive bleeding after delivery; no separation of placenta after birth.
Defective decidual layer allows placenta to attach to myometrium.
A/w prior c section
What is placenta previa?
Painless bleeding in any trimester.
Attachment of placenta to lower uterine segment.
May occlude internal os
a/w prio c section
What is an ectopic pregnancy?
Earliest complication.
Pain with or without bleeding.
Most often in fallopian tubes.
Suspect in increased hCG and sudden lower abdominal pain; mistaken for appendicitis.
Most common breast tumor in women under 25?
Fibroadenoma
Most common breast tumor in postmenopausal women?
Invasive Ductal Carcinoma
Most common breast tumor in premenopausal women?
Fibrocystic Change of Breast
Most common form of breast cancer?
Invasive Ductal Carcinoma
What breast pathology is a/w small, mobile, firm mass with sharp edges in a 24 yo woman?
Fibroadenoma
What breast pathology is a/w leaf like projections histologically?
Phyllodes Tumor
What breast pathology is a/w signet ring cells?
Lobular Carcinoma in situ
Invasive lobular cancer
What breast pathology is a/w the loss of e-cadherin cell adhesion gene on chromosome 16?
Invasive lobular carcinoma
What breast pathology is a/w ER(+) and PR(+)?
Lobular Carcinoma in situ
What breast pathology presents with nipple discharge?
Intraductal Papilloma
What breast pathology is a/w eczematous patches on the nipple?
Paget's disease
What breast pathology is a/w multiple bacterial fluid filled lesions with diffuse breast pain?
Fibrocystic changes of breast
What breast pathology is a/w a firm, fibrous mass in a 55 yo woman?
Invasive Ductal Carcinoma
A 58 yo postmenopausal woman is on Tamoxifen; what is she at increased risk of acquiring?
Endometrial Carcinoma
What is the two-cell theory of estradiol production?
Theca Cells make androstenedione stimulated by LH
Granulosa cells make estradiol from androstenedione stimulated by FSH
What are the target cells of LH?
Leydig Cells
Theca Cells
What are the target cells of FSH?
Sertoli Cells
Granulosa Cells
Production of thick mucus that inhibits entry of sperm into uterus, progesterone or estrogen?
Progesterone
Induces LH surge, progesterone or estrogen?
Estrogen
Uterine smooth muscle relaxaition, progesterone or estrogen?
Progesterone
Follicle growth, progesterone or estrogen?
Estrogen
Maintenance of pregnancy, progesterone or estrogen?
Progesterone
Hepatic synthesis of transport proteins, progesterone or estrogen?
Estrogen
Withdrawal leads to menstruation, progesterone or estrogen?
Progesterone
Drug to inhibit prolactin secretion?
Bromocriptine
When does beta hCG appear in urine during pregnancy?
2 weeks post conception
4 weeks after last menstrual period
What hormonal changes are seen during menopause?
Decreased estrogen leading to Increased FSH, LH, and GnRH