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Glomerular filtration pressure is opposed by both plasma ____ pressure & renal ____ Pressure.
plasma oncotic & Renal interstitial pressure
Glomerular capillaries are ____ Proportional to efferent arteriolar tone & ____ proportional to afferent arteriolar tone.
Explain the countercurrent multiplier?
Descending limb/thin ascending limb is permeable to Na+, CL-, H20, & Urea.
Thick ascending limb is permeable to H20, urea, actively reabsorbs Na+/CL- generating an osmotic gradient.
Explain what is involved in the cortical portion of the collecting tubule?
Principle Cells (P cells) secrete K+, participate in aldosterone mediated Na+ reabsorption.
Intercalated cells (I cells) Acid base regulation
Explain the medullary portion of the collecting tubule?
Site of action of ADH
Dehydration = ADH secreation
Responsible for acidifying urine (contains more I cells than P cells)
What does renin do when it is released by the kidney into the blood stream?
Renin released into the bloodstream acts on angiotensinogen to form angiotensin I. Conversion of ACE in lungs to form angiotensin II. Angiotnesin II plays a major role in BP regulation/aldosterone secretion.
RBF/GFR kept constant by afferent arteriolar vasoconstriction/vasodilation.
Just an important fact to know
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