Explain the medullary portion of the collecting tubule?
Site of action of ADH Dehydration = ADH secreation Responsible for acidifying urine (contains more I cells than P cells)
What does the juxtaglomerular apparatus do?
Secretion of renin
What are juxtaglomerular cells innervated by?
These cells are innervated by the SNS
What does renin do when it is released by the kidney into the blood stream?
Renin released into the bloodstream acts on angiotensinogen to form angiotensin I. Conversion of ACE in lungs to form angiotensin II. Angiotnesin II plays a major role in BP regulation/aldosterone secretion.
Kidneys are the ONLY organs for which ____ consumption is determined by blood flow.
Combined blood flow in both kidneys is ____% of total CO?
____% of RBF goes to cortical neprhons.
Renal cortex has ____ blood flow, extracting little O2.
Renal medulla has low blood flow, high ____metabolic activity.
How many ML/min is RBF?
Normal values for men/woman GFR?
Men 120 mL/min Women 95 mL/min
What is a practical measurement of GFR?
GFR is dependent on tones of afferent/efferent arterioles. T or F?
Afferent arteriolar tone appears to maintain GFR constant over a wide range of BPs? T or F?
Where does auto regulation of RBF normally occur at?
Blood flow is generally decreased at MAP <___?
70 mm Hg
RBF/GFR kept constant by afferent arteriolar vasoconstriction/vasodilation.