Question types

Start with

Question limit

of 54 available terms

Advertisement Upgrade to remove ads
Print test

5 Written questions

5 Matching questions

  1. Granzymes
  2. IL4
  3. MHC restriction
  4. Sensitization
  5. Neutralization by Ig's
  1. a The first stage in type 1 allergic response. Allergen in exposed to person. Processed and presented to t-cells. Il's produced which act on b-cells to produce IgE activating mast cells.
  2. b Cytokine secreted by TH1-cells to initiate proliferation and clonal expansion of B-cells.
  3. c Are serine esterases present in the granules of a cytotoxic t cells and NK cells. On entering the cytosole of the target cell granzymes induce apoptosis of the target.
  4. d When T-cell recognizes both peptide and MHC molecule, occurs during positive selection of T-cell maturation causing the T-cell to lose one of its two co-receptors CD4 or CD8.
  5. e involves the Ig binding tightly to the pathogen to prevent interaction with it receptor on humans. The Ig's crosslink pathogens. The neutralized pathogen once bound is phagocytosed.

5 Multiple choice questions

  1. NK cells are a subset of leucocytes capable of recognizing cell surface changes on virally-infected cells. NK cells bind to such infected cells and kill them. Also sometimes effective against transformed (tumor) cells.
  2. Immediate type hypersensitivity response, antibody mediated IgE, soluble antigen, mast cell effector
  3. Large signal transduction complex that is associated wit the T-cell receptor in the T-cell membrane. Contain Intracellular ITAMs domains.
  4. Drive b-cells to differentiate and produce immunoglobulins of all other types. Also responsible for initiating B-cell responses by activating naïve B-cells to proliferate and secrete IgM. Leads to Humoral immunity.
  5. Stimulated b-cells that are proliferating in the germinal centers.

5 True/False questions

  1. FabLymphocyte Function Associated Antigen-1. An integrin expressed by all t-cells it is important for to allow for binding to cell adhesion molecules expresses on extracellular matrix.


  2. EpitopeThe classes of an immunoglobulins.


  3. Double negative thymocyteThe recognition of non self MHC molecules by T-cells.


  4. Innate ImmunitySecond line of defence non-adaptive/non-specific immunity. Involve the non-specific destruction of pathogens via macrophages, neutrophils, NK cells and circulating proteins of complement and acute phase proteins.


  5. IL2Cytokine secreted by TH1-cells to initiate proliferation and clonal expansion of B-cells.