19 terms

Renal

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most common nephrotic in kids
minimal change
foot process effaced
loss of albumin
triggered by recent inx/ immune prob
tx - steroids
granular pattern of IC; diffuse capillary thickening
membranous glomerulonephritis
spike & dome
due to drugs, inx, SLE, tumors
MCC adult nephrotic syndrome
membranous glomerulonephritis
granular patter of IC, hypercellular glomeruli
acute post strep glomerulonephritis

type 3 rxn
seen in kids
peripheral & periorbital edema & dark urine
hypercellular glomeruli
acute post strep glomerulonephritis
IgA, IgM, IgG, C3 deposited in mesangium
IgA nephropathy
related to Henoch-Schonlein dz
Kimmelstein Wilson lesions
nodular glomerulosclerosis

Diabetic glomerulonephropathy
due to nonenzymatic glycosylation of GBM
Nephrotic syndrome a/w HBV & HCV
membranoproliferative glomerulonephritis
tram trak appearance
nephrotic syndrome a/w HIV
focal segmental glomerulosclerosis
anti-GBM AB, hematuria, hemoptysis
GoodPastuers
subendothelial humps & tram track appearance
membrano-proliferative glomerulonephritis
nephritis, deafness, cataracts
Alport syndrome
Crescentic/rapidly progressive glomerulonephritis
cresent shaped, full of fibrin and plasma proteins.

Goodpastures - AB to GBM - linear IF
wegners granulomatosis - cANCA
microscopic polyangiitis- pANCA
GoodPasteures
type II
hematuria/hemoptysis
male
segmental sclerosis and hyalnosis
focal segmental
purpura on back and arms, IgA nephropathy
Henoch-Schonlein
wire loop on LM
SLE nephropathy
apple green & congo red
amyloidosis
spiking on GBM due to electron dense subepithelial depositis
membranoproliferative glomerulonephritis