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Cardiopulmonary Pharmacology: Drug Actions

cardiopulmonary pharm ppt, pgs 1-5
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Pharmacology
study of drugs; their origin, nature, properties and effects
Pharmaceutical Phase
method by which a drug is delivered (route of administration and drug form)
Pharmacokinetic Phase
the time required for drug absorption, drug action, drug distribution in the body and metabolization and excretion of drug.
Pharmacodynamic Phase
refers to the mechanism of action by which a drug causes its therapeutic effect
Tolerance
when increased amounts of a drug are needed to produce the desired effect, possibly due to increased enzyme levels related to enzymatic activity that develops over a period of time
Tachyphylaxis
rapid development of drug tolerance
Cumulative Effect
exaggerated response and a possibly toxic situation
Additive Effect
an exaggerated response, occurs when two or more drugs are administered with the same effect on the body
Synergy
when two or more drugs produce an effect or response that neither could produce alone
Potentiation
either when two drugs produce an effect that is greater than what they usually produce when given alone or when one drug enhances the effect of another drug
Antagonism
when two drugs have opposite effects