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Events Leading to Neurotransmitter Release
AP passes along an axon and over surface of synaptic knob
synaptic knob membrane becomes permeable to Calcium ions and diffuse inward
in presence of calcium ions, synaptic vesciles fuse to synaptic knob membrane
synaptic vesicles release neurotransmitter by exocytosis into synaptic cleft
synaptic vesicles become part of membrane
the added membrance provides material for endocytotic vesciles