Host: Canine, feline, zoonosis
Adults: long, slender, 20-30cm L
LC: Adults in pulmonary artery, female releases microfilariae in blood, mosquito ingests microfilariae with blood meal, microfilariae develop in mosquito to infective larvae, mosquito bites and transmits infective larvae.
PPP: 7-9mo Adults survives for years, and can be patent for 5-7yr in dogs.
SOI: Pulmonary artery, right ventricle, caudal vena cava
Path: Severe heart and lung disease changes, endarteritis, congestive heart failure, caval syndrome
CS: Dysfunction of lungs, heart, liver, & kidneys, cough, exercise intolerance, dyspnea, abnormal heart and lung sounds, hepatomegaly, syncope, as cities, death, hemoglo binemia, hemoglobinuria.
Dx: radiology, angiography, u/s, serology, antigen tests -- ELISA & immunochromatographic test
Tx: MCLs, prevention