Pyrimidine Analog Antimetabolites .15.(41)

inhibit pyrimidine synthesis
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Fluorouracil
Adrucil
Fluorouracil
Efudex
Fluorouracil
Antineoplastic: pyrimidine antimetabolite
(cell cycle−specific) causes "thymine−less" cell death; used mainly for solid or superficial tumors.
Tox: GI distress, myelosuppression