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PNS activity results in _______ heart rate
SNS activity results in _______ heart rate
Example of an organ that relies on both PNS and SNS to function normally
Penis (PNS --> erection, SNS --> ejaculation)
When a system is dominantly innervated by one component of the ANS, if you block both components, what is the overall result
The outcome will appear as if only the dominant innervation had been blocked
(ex. is ganglionic blockers)
If an organ is dually innervated by the PNS and SNS, blocking one or the other will result in
The other becoming temporarily dominant
(ex. administration of atropine in an elderly male results in blocking the PNS and retention of urine in a man that otherwise may already have BPH, thus worsening the condition and prventing urination completely)
Effect of _________ on the eye:
Loss of accomodation
Loss of pupil constriction
Drugs which interract with Nicotinic receptors, do so primarily at what location
Preganglionic nerves of the SNS innervate the Adrenal Medulla with ACh released onto which receptors
Disease --> reduced NE w/ increased E from Adrenal Medulla
(reduced production of NE from E is a component of the disease)
SNS plays no role in which intraoccular eye muslce
(so no drug which interracts with SNS receptors will have any effect on accomodation of the eye)
ACh-ase hydrolyses ACh into Acetate and Choline, so that Choline may be
Reuptaken by presynaptic neuron and reused
Nicotinic muscular receptors are only in the neuromuscular junction, while Nicotinic Nerveous receptors are located where
When M2 receptors open, what biochemistry results
dec Adenylyl Cylcase --> dec cAMP --> K+ channels open --> K+ exit
Vasodilation is mediated by Nitric Oxide when arginine is transformed into NO via Nitric Oxide Synthase. NO is used as a substrate for Guanylyl Cyclase in smoo musc for what reaction
GTP --> cGMP
Smoo musc relaxation and vasodilation results in decreased blood flow to heart and
ACh in GI on M3 -->?
^ tone and peristalsis
^ GI gland and lacrimal gland decretion
Accomodation (for near vision) occurs when
Ciliary muscle contracts --> zonule fibers relax --> lens bulges
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