S4 Mini II pathology

Sessile Polyp (Adenocarcinoma)
Pedunculated Polyp (Adenocarcinoma)
Inflammatory Pseudopolyps in Ulcerative Colitis
Inflammatory Polyp (prolapse type)
Juvenile Polyps
Juvenile Polyps
Peutz-Jeghers Syndrome, hamartomatous polyp of the small bowel pretty normal gland, just malformed, are not dysplastic
Small Intestinal PJ Hamartomatous Polyp
small bowel, looks almost like normal mucosa, just disorganized
Colonic PJ Hamartomatous Polyp
Mucosal "freckles" in PJ syndrome
Colonic Hyperplastic polyp
no malignant potential
happens anywhere in the colon
serrated architecture of the glands, smooth out at bottom of the crypt
cross-section looks kind of like a star
Sessile Serrated Adenoma
usually right colon
usually >1 cm
dilated crypts
Tubular adenoma
Tubular Adenoma (TA)
looks like low grade dysplasia in ulcerative colitis
- stratification of nuclei
- bluer than normal
- darker than normal
- regular-shaped glands
- not complex back-to-back glands as seen in high-grade dysplasia
Villous Adenoma
Villous Adenoma
Tubulovillous Adenoma
High Grade Dysplasia
Carcinoma of Cecum
colonic adenocarcinoma right side cancer in cecum fecal flow could still go sometimes do not present until very late
Rectosigmoid adenocarcino
colonic adenocarcinoma
left side rectosigmoid cancer stenosing
tend to cause symptoms, maybe even obstruction at an earlier stage
Moderately Differentiated Adenoma
colon cancer
- complex glands
- columnar cells
- debris in center
- fibrotic and pink dysplasic stroma good evidence for invasion
of carcinoma
Dirty Necrosis in AdenoCa
Poorly diff Adenocarcinoma
Mucinous Adenocarcinoma
- light-coloured mucin
- islands of epithelium floating in the mucin
- in the colon mucinous adenocarcinoma has worst prognosis
Metastatic Carcinoid in Liver
intestinal carcinoid
Gastrointestinal Stromal Tumors (GIST) of the Intestine
Gastrointestinal Stromal Tumors (GIST) of the Intestine
appendiceal carcinoid
appendiceal carcinoid
mucinous cystadenoma
mucinous cystadenoma
Pseudomyxoma Peritonei
If gallons of mucin are seen, look for appendix, that's probably where it's coming from
Pseudomyxoma Peritonei
specimen of blood mucin
Implants from Mucinous Cystadenocarcinoma
malignant if there are islands of epithelial cells within mucin