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Result of nociceptor activation in thoracic or abdominal tissue; can be pancreas, liver, GI poorly localized... cramping.
From Greek word Ethos, means conduct, customs and character. A process of deciding best course of action when faced with conflict.
Phase 1 Clinical Trials
Assist in developing safe drug levels and schedules of new drug using human subjects.
Phase 2 Clinical Trials
Usually focus of particular type of cancer, study safety and effect of drug on human body.
Phase 3 Clinical Trials
Compare new drug with standard therapy; usually large number of participants.
process of transmitting information received on the cell membrane to the cell's nucleus.
Overproduction of RAS oncogenes have been identified in what cancers?
Pancreatic, colorectal, lung, and thyroid.
Inherited Cancers occur via...
carcinogenic mutation in germ cells. Account for 10% of cancer in the USA
Combination therapies that include etoposide and alk. agents...
cause increase FSH levels and azoospermia or olgiospermia in 30-40% mals. Test funct. may be normal if tx with etoposide and nonalkylating agents (vincrustine, doxorubiein)
granulocyte stimulating factor- stimulates myloid line; increases WBC's; starts 24 hours post chemo for 3-14 days.
Increased risk DIC
leukemia, lymphoma, buliany, breast, colon, gastric, lung, pancreatic, prostate, melanoma
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