36 terms

Drug suffixes

pharmacology, First Aid 2012, DIT
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-conazole
antifungal - inhibit ergosterol synthesis
-cillin
penicillin (beta lactam - inhibit peptidoglycan cross-link)
-cycline
antibiotic: protein synthesis inhibitor (inhibit translation by binding 16S of 30S ribosomal subunit, preventing aminoacyl-tRNA binding)
-navir
protease inhibitor
-triptan
5-HT 1B/1D agonist (migraine)
-ane
inhalational general anesthetic
-caine
local anesthetic (membrane stabilizing - inhibit voltage-gated sodium channels)
-operidol
butyrophenone (neuroleptic)
-azine
phenothiazine (neuroleptic, antiemetic)
-barbital
barbiturate (bind GABA-A receptor at beta subunit)
-zolam
benzodiazepine (promote GABA binding)
-azepam
benzodiazepine (promote GABA binding)
-etine
SSRI
-ipramine
TCA (most act as SNRIs)
-triptyline
TCA (most act as SNRIs)
-olol
Beta antagonist
-terol
Beta-2 agonist
-zosin
Alpha-1 antagonist
-oxin
cardiac glycoside (inotropic agent)
-pril
ACE inhibitor
-afil
erectile dysfunction (phosphodiesterase-5 inhibitor, increases cGMP)
-tropin
pituitary hormone
-tidine
H2 antagonist
-dronate
bisphosphonate (kill osteoclasts)
-sartan
ATII receptor blocker (ARB)
-chol
muscarinic agonist
-stigmine
anti-acetylcholinesterase (indirect ACh agonist)
-mustine
nitrosourea (DNA alkylating agents - brain tumor tx)
-curium/-curonium
non-depolarizing neuromuscular blocker (acetylcholine antagonists - paralytics)
-statin
HMG-CoA reductase inhibitor (lower LDL)
-glitazone
thiazolidinedione (TZD - activate PPAR - increase insulin sensitivity)
-bendazole
anti-helminthic (inhibit tubulin polymerization)
-dipine
dihydropyridine calcium channel blocker
-prost
prostaglandin analog
-phylline
methylxanthine (competitive nonselective phosphodiesterase inhibitor, adenosine antagonist - inotropic, chronotropic, relax bronchial smooth muscle)
-mab
monoclonal antibody