Virulence Factors of S. aureus
1. Coagulase Positive (Hiding in the clot), Kinase, Hyaluronidase (hyaluronic acid - invades deeper), Beta hemolytic - lysis cells; Eats them Up!
2. Protein A - Binds stem of igG preventing opsonizations and complement
3. Slime Layer - Inhibits phagocytes, allows attachment to artificial surfaces (catheters, shunts, heart valves, artificial joints - loves plastic)
4. Beta lactamase - Brakes beta lactam ring of penicillin = resistant to penicillin and other Antibiotics, 90% of strains are resistant