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History of Lab animals
Terms in this set (60)
Laboratory Animal Science refers to....
The scientific and technical information and techniques that apply to laboratory animal care
What does Laboratory Animal Science include?
Husbandry, nutrition, behavior, health, production, and management of laboratory animals
What did Aristotle do?
Observed animals and laid the foundation for comparative anatomy and embryology
What did Gales do?
Established the principal for experimental research and started the scientific process
Who was the first Laboratory Animal Veterinarian?
Dr. Simon D. Brimhall
What did Dr. Brimhall do?
He helped to establish colonies, investigated laboratory animal diseases and participated in independent research
What happened in 1950?
Marked the resurgence of humane awareness and established the Laboratory Animal as a recognized field because the government started funding animal medical research
Animal Care Panel (ACP) was formed
What was the goal of the ACP?
To create a national organization professionally concerned with the production, care and study of laboratory animals
What happened in 1967?
ACP became AALAS (American Association for Laboratory Animal Science)
Where is the statue that symbolizes scientists gratitude for sacrifices of lab rats?
The Institute of Cytology and Genetics in Novosibirsk, Russia
Who was the first dog to enter space? When?
Laika, 1957 aboard Sputnik II
Which physiologist used dogs to study?
American Association for Laboratory Animal Science
What three levels of technical competence does AALAS certify?
Assistant Lab Animal Tech (ALAT)
Lab Animal Tech (LAT)
Lab Animal Technologist (LATG)
What does a ALAT do?
Entry level, basic understanding of laws/ ethics, responsible for important daily tasks of animal husbandry
What does a LAT do?
First-level supervision, training
Daily husbandry/ record/ diagnostic tasks
Current knowledge: husbandry, research methods, humane treatment of animals
What does a LATG do?
Senior level team members, training, management, supervisory
What does AALAS do?
Provides communication in the field
Publishes 2 journals
Certifies Training Technicians
Association for Assessment and Accredation of Laboratory Animal Care International
What does AAALAC do?
Provides Voluntary site visit and evaluation for accreditation.
National Association for Bio-medical Research
What does NABR do?
Organization that represents the interest of the community in the area of legislation through political lobbying
American Veterinarian Medical Association
What does the AVMA do?
Parent Organization for all Veterinarian. Publishes 2000 Report of the AVMA Panel on Euthanasia.
Establishes all methods of euthanasia and animal research
American College of Laboratory Animal Medicene
What does ACLAM do?
Board Certifies Veterinarians to allow them to be called Diplomat of the American College of Laboratory Animal Medicine.
Name 4 Animals Activist organizations
PETA- People for Ethical Treatment of Animals
Doris Day Animal League
ALF- Animal Liberation Front
IDA- In the Defense of Animals
Ethics is defined as...
1) The principal of honor and morality
2) Accepted rules of conduct
3) Moral principals of an individual
What are the 3 R's of research?
Replacement, Refinement, Reduction
Of animals by cell or tissue culture or by mathematical models where possible
Of procedures to minimize stress or pain to animals when possible
To minimize number of animals that will serve a useful purpose, yield statistically sound data and produce scientific benefit
Individuals that have no problem "punishing" animals. Luckily, there is little intentional animal cruelty in the US. There is still considerable animal cruelty due to ignorance, however. Starvation often associated
Some people abuse animals and use them only for their benefit. No problem with dog fighting, bull fighting, cock fighting, poaching, trapping, target shooting
Expresses the responsibility to protect animals from harm and ascribes to the idea of humane ethics. Use animals for food and research, but minimize suffering and advocate a fast, painless death..
Rights of animals should be guaranteed and that animals should not be eaten or used for research or sport. Opposed to research, hunting and trapping. Opposed to killing, except to reduce suffering
Most extreme. Try to eliminate all types of animal use by any means necessary (bombs, murder, arson). Believe their cause is so grand that it is higher than the law.
Random Source Animals
Procured from USDA Class B dealers
Individual Owners or breeders
Pounds and shelters
Procured from USDA Class A dealer/privately owned research colonies
Raised and bred specifically for research
What amount of cats and dogs are euthanized in shelters each year?
What percentage of research do Nonhuman primates make up in research in the US?
Less than 1% of USDA regulated animals
What diseases did chimpanzees help?
Polio and Hepatitis B vaccines
What is the goal of research?
To gain new knowledge with which to improve the future of people and animals
What does the research proposal include?
Detailed outline of a proposed research.
Why Animals are needed.
How will the animals will be housed and cared for via the animal use protocol.
Who is the Research Proposal reviewed by?
develops idea and prepares the protocol.
Co-investigator & research technicians
performs specific research tasks required for the protocol.
Laboratory Animal Technicians
perform many animal care functions critical to the maintenance of healthy animals
Laboratory Animal Veterinarian & technicians
Maintain animal colony health and insure compliance.
Commercial Animal Supplier
Animal suppliers provide / breed animals that meet specific research requirements
Institutional Animal Care and Use Committee
What does IACUC do?
They can exert necessary controls to insure quality animal care.
They can require investigators to make modification or can refuse to permit the project to begin or continue.
IACUC committee includes the CEO, scientist and non scientists
What does the Animal Welfare Act do?
Regulates the use of warm bloodied vertebrates (primarily Cats, Dogs & Primates) and enforces the research facility to...
Register with the USDA
Maintains individual records via tattoo or tag.
Submit accounts of animals involved in a project which results in pain and/or destruct.
Meet or exceed standard of sanitation.
Provide adequate veterinarian care.
Use the proper Shipping Container.
Training for Scientist, Animal Technicians, and others using animals.
Exercise of Dogs requirements.
Psychological well-being of non human primates.
Requiring animal anesthetic and analgesics for procedures.
Prohibiting more than one major procedure per animal.
Inspection of the facility by the IACUC.
Establishment of the IACUC.
Guide for the Care and Use of Laboratory Animals outlines...
Adequate Veterinary Care
Surgical & Post Surgical Care
Acceptable Euthanasia Techniques
Facility Construction Guidelines
Institute for Laboratory Animal Research
What does the ILAR do?
Develops guidelines and disseminates information on scientific, technological, and ethical use of animals
Develops resources for research, testing, and education
Promotes high-quality humane care and appropriate use of animals
American Society of Laboratory Animal Practitioners
What does ASLAP do?
Professional organization to exchange ideas, experiences, and knowledge among veterinarians
Spokesperson for laboratory animal practitioners within the AVMA
Foundation for Biomedical Research
What does the FBR do?
Promotes public understanding and support for humane and responsible use of animals in scientific and medical research
Provides information to teachers, students, media, general public
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