Pharmacology Chapter 1 Saunders
Terms in this set (13)
What are the three phases of drug action?
Pharmaceutic, Pharmacokinetic and Pharmacodynamic
Pharmaceutic phase (dissolution)
A solid drug is disintegrated into smaller particles in GI Tract before absorption.
What are some fillers (excipients) that are added to penicillin so that the drug can take on a certain size and shape to enhance drug dissolution?
Potassium (K) and Sodium (Na)
The time it takes for a drug to disintegrate.
Drugs are generally disintegrated faster in?
Acidic fluids with a PH of 1 or 2 rather than alkaline fluids
The process of drug movement to achieve drug action.
What are the four processes of the pharmacokinetic Phase?
Absorption, distribution, metabolism(or biotransformation), and excretion (or elimination)
requires carrier (such as enzyme or protein) to move drug against concentration gradient...
...Uses process of diffusion (movement from higher to lower concentrations) in order to absorb
...absorbed by cells carrying drugs across their membranes by engulfing the drug particle
lipid fat and protein
GI Membrane is mostly composed of what?
what kind of drugs need a carrier?
What type of drugs pass rapidly thru the GI tract
Lipid soluble and non ionized
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