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Pr: morphine (Duramorph)
Action: stimulates MU and Kappa receptors
Use: analgesia, pre-anesthetic, relief of SOB, PCA pump
Ad eff: N/V, dizzy, dependance, constipation, sedation, restlessness, tolerance
Nsg C: assess for potential dependency. educate pt about PCA pump, assist w/ activity.
Monitor pain level using scale before and after.
Monitor VS= resp around the clock Hold<12, <10 give Narcan
Monitor urine output for retention, monitor BM
Monitor constipation (Narcan is the antidote)
Pr: naloxone (Narcan)
Action: Block MU and kappa receptor
Use: reverse respiratory depression
Ad eff: increased cardiac workload, withdrawal symptoms for opiate abusers
Nsg C: have resuscitate equipment available, assess VS and respirations q3-5min, assess pain level, monitor CV status
Pr: Ibuprofen (Motrin)
Action: inhibit cox 1 to prevent formation of prostaglandin (pain/inflam)
use: analgesia, antipyretic, anti-inflammatory
Ad eff: GI upset, acute renal failure
Pr: aspirin (Acetylsalicylic acid) ASA
Action: inhibits prostaglandin formation, anticoagulant activity, Cox 1 inhibitor
Use: antipyretic, analgesic, anti-inflam, anticoagulant
ad eff: GI upset, and bleeding (not to be taken w/alcohol) many increase oral hypoglycemic agents effects (lower BS)
NSAID selective Cox 2
Pr: celecoxib (Celebrex)
Action: inhibition of cox 2
Use: analgesia, antipyretic, anti-inflam. esp RA and OA
AD eff: mild GI symptoms, pain, D, dyspepsia, flatulence, N
Pr: acetaminophen (Tylenol)
Action: pain relief mechanism unknown, fever by vasodialation of vessels
Use: mild to mod pain and fever relief
Ad eff: uncommon if taken as directed, Hepatotoxic-dont take w/alcohol
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