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5 Written questions

5 Matching questions

  1. Neurohemal organ
  2. Ghrelin
  3. In vivo reprogramming of adult pancreatic exocrine cells to B cells
  4. Xanthophores
  5. Fxs of 1,25(OH)2D3
  1. a yellow/orange/red pigments; carotenoids/pteridines; located in dermis
  2. b 3 transcription factors incude insulin cells in adult mouse pancreas in vivo; induced new B cells originate from differentiated exocrine cells; endogenous and induced B cells re indistinguishable in morphology and ultrastructure; incuded new B cells remodel vascularature adn amliorate hyperglycemia; STZ destroys B cells
  3. c stimulates GH release from AP; produced in stomach, sm intestine, hypothalamic neurosecreatory neurons; regulates feeding behavior/energy homeostasis
  4. d axon endings, vascular bed, pituicytes
  5. e Intesting (stimulate sythesis of Ca-binding protein, inc # Ca channels) :: Kidney (inc Ca reabsorption) :: Bone (accretion of new bone during remodeling) :: PT gland ( inhibits PTH synthesis)

5 Multiple choice questions

  1. rickets (failure in kids) osteomalacia (in adults) Paget's dz ( weak bones due to excessive osteoclasts)
  2. stain with basic dyes (TSH, FSH, LH, ACTH)
  3. increase insulin sensitivity; levles inversely related to body fat; acts wtih insulin to inc glucose uptake and metabolism in muscle and block glucose formation in liver; decreased in DM2
  4. GI absorption; storage in bone as Ca10(PO4)6(OH)2 (80% Ca in bone); relationship to P: [Ca] x [PO4] = K; PO4 stored in bone/tissue not carefully regulated
  5. produce more leptin to eat less

5 True/False questions

  1. aMSH absentdec in cAMP increase free Ca2+ causing contraction of melanofilaments whic hpull melanosomes into smaller area, causing lightened skin


  2. Pars nervosamajor part of neural tissue


  3. Insulin sxr2 chains (A chain, 21AA, B chain, 30 AA), 2 inter-chain disulphide bridges


  4. GH related dzDwarfism (underproduction); Gigantism (excess GH, linear bone growth); Acromegaly (excess GH in adults)


  5. Gastrin fxnsPrimarily to increase HCL (release of H+ from stomach parietal cells) directly and indirectly (via stimulataing HCL cells to release histamine that stimulates the parietal cells via H2 receptors); inc calcitonin release and gastric mucosal growth