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5 Written questions

5 Matching questions

  1. GIP - gastric inhibitory peptide
  2. Glucosuria
  3. Hyperlipidemia
  4. Polydipsia
  5. OT (oxytocin) release
  1. a Inc thirst due to dehydration
  2. b glucose exceeds tubular max, excess remain in urine
  3. c gluconeogenesis leads to inc FFA and glycerol; dec VLDK clearance due to dec lipoprotein lipase activity (requires insulin)
  4. d neuroendocrine reflex - result of sensory input to SC -> brain; neuron depolarization in AP of pars nervosa -> Ca entry -> exocytosis of OT; AP reach axon tips in 0.5-1.5m/s; ex of stimulus released coupling: rapid response
  5. e aka glucose-dependent insulinotropic peptide, enterogastrone; made in K cells, small intestine; stimulus for release are fats and glucose

5 Multiple choice questions

  1. source of melanotropins; present in cyclostomes, amph, reptile and most mammals (well defined pars intermedia or lobe wtih MSH secreting cells); not present in birds, whales/dolphins, adult humans (present in fetus)
  2. biologically active horm affecting Ca, synthesized from Vit D3, Vit D3 from diet/skin exposed to UV light
  3. stimulate a-MSH release which binds to melanocortin-4 receptor, decreases appetitie/eating
  4. gallbladder contractions, relaxation of sphincter of oddi, inhibition of gastric emptying, inc pancreatic enzyme secretion and bicarb secretion, stimulates growth exocrine pancreas
  5. component of rennin angiotensin system, acts on brain to stimulate AVP release

5 True/False questions

  1. Corticotropinstimulates GH release from AP


  2. Factors inhibiting glucagon releaseatrial natruiuretic factor (ANF), ethanol, low temp


  3. GnRH fxn (gonadotropin RH)decapeptide; fxns to release FSH,LH; neuroregulation of GnRH: dopaminergic neurons stimulate secretion, encephalinergic neurons inhibit secretion


  4. Hypoparathyroidismdec in release of PTH; causes tetany and convulsions; tapping facial muscles detects latent tetany; pseudohypoparathyroidism - nl PTH levels, low Ca levels, failure to generate cAMP


  5. Morphological color changeinduce ovulation; treat oligospermia, constant exposure causes gonadotrope desensitization; GnRH longacting analogs = antifertility agent