5 Written questions
5 Matching questions
- ototoxicity and nephrotoxicity
- a SE of this antimalarial include cinchonism (tinnitus, visual problems), hypotension, and acute circulatory failure; thrombocytopenia, hypoglycemia, and fetal abnormalities
- b problems of aminoglycosides include ____________ (which is commonly irreversible) and ____________.
- c Lariam, Fansidar, and Halfan. etc. are primarily used as antimalarials if ___________ resistance
- d originally approved for acute exacerbation of bronchitis, sinusitis, and community-acquired penumonia; however the FDA has recently removed bronchitis and sinusitis from the approved indications, leaving only community acquire pneumonia on the approved list.
- e antifungal that is available IV and topical only. IV use is primarily reserved for severe, progressive, potentially fatal infections. It is the big gun of antifungals.
5 Multiple choice questions
- Administration of antibiotics based on the practitioner's judgment of the pathogens most likely to be causing an apparent infection; it involves the presumptive treatment of an infection to avoid treatment delay before specific culture information has been obtained.
- New class of drugs that inhibit bacterial growth by interrupting protein synthesis (bacteriostatic)
- There has been a recent push to reduce ___________ use to prevent resistance.
- these drugs are usually bacteriocidal, they weaken the bacterial cell wall making it susceptible to influx of water and lysis. It has a problem of resistant strains of bacteria. A major problem is hypersensitivity. Depending on the drug and dosage, it can cause varying degrees of neurotoxicity, nephrotoxicity, and hepatotoxicity.
- antimalarial most commonly used for both acute treatment and prevention
5 True/False questions
prophylactic therapy → ___________ therapy is not very effective in many instances, particularly for the "routine" viral infections such as minor flu, colds, etc.
tetracyclines → risk for superinfections, especially C. Difficile infection (pseudomembranous colitis) and candida
HIV → sulfonamides are primarily used for UTI and are drugs of choice for _____
gentamicin, neomycin, kanamycin, streptomycin, and tobramycin → Primary SE with most of the azoles are ___________ and ____-_____ ____________ due to the inhibition of P450 hepatic enzymes.
antiviral → __________ for influenza should be restricte to those at high risk for complications.