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Terms in this set (60)
Which of the following genetic disorders is created by a translocation between chromosome 9 and chromosome 22?
Chronic myelogenous leukemia
Cystic fibrosis is caused by a gene encoding a protein involved in ________.
A limitation of retrovirus-mediated gene transfer means that ________
Retroviruses integrate DNA randomly in the genome
Most current gene therapy trials target _____________.
Which of the following is an example of in vivo gene therapy?
Using retroviruses to deliver therapeutic genes directly into a patient
Pluripotent stem cell is capable of producing active neurons.
Pink eye is caused by ___________.
List two particles that are used in nanotechnology.
Huntingtin protein usually has over 40 polyglutamines.
Herceptin is an antiviral drug
A mutation in the adenosine deaminase gene is the cause of what genetic disease?
Severe combined immunodeficiency
Which of the following descriptions of embryonic stem cells is incorrect?
They are present in all adult tissues
Proto-oncogene is a normal gene that promotes cell division.
Which vehicles are often used for gene therapy to carry a healthy gene?
The small molecule of colchicine is a(n) ____________________.
________ is the use of genes for treating human genetic disorders.
What form of gene therapy involves direct injection of DNA into cells within the body?
Proteins that are produced in a diseased tissue and can act as a means of tracking a disease progression (such as Prostate-specific antigen in prostate cancer) are known as ________.
Dopamine is a _______________.
Which of the following is the source of embryonic stem cells?
Prions are infectious proteins which promote misfolding of normal proteins.
Which of the following is used to treat osteoporosis?
Transgenic salmon engineered to grow faster than nontransgenic strains contains extra copies of the ________ gene.
Growth hormone (GH)
Polyploid organisms ________.
Have an extra complete sets of chromosomes
One of the most common organisms used to produce knockouts is ________.
Which aquatic organism derived molecule is used to treat breast cancer?
In what phase of clinical trials are animals used?
In a gene knock-in experiment, ________.
The animal gene of interest is replaced with the human counterpart gene
Which of the following transgenic techniques requires Embryonic Stem cells to be collected from the inner blastocyst?
Embryonic stem cell method
Which of the following human recombinant protein is first produced in goat.
Embryo twinning refers to ________.
A cloning step that involves splitting embryos in half
The BRCA1 gene in humans is similar to the BRCA1 gene in dogs.
What is the name of the positive selection marker gene used in transgenic animals?
Conotoxin is an analgesic.
List two genetically modified fish species.
1. aquadvantage atlantic salmon
Monoclonal antibodies ________.
Are highly specific to a particular antigen
________ animals have been genetically engineered so that a specific gene is disrupted and rendered nonfunctional.
Which of the following techniques has been used to clone sheep, cats, cows, and several other types of mammals?
Somatic cell nuclear transfer
Which of the following transgenic techniques requires no vector to be used?
Pronuclear injection method
________ animals contain an inserted and functional gene from another source.
Which of the following is a binary vector?
All of the above
Agrobacterium rhizogenes plasmid contains the rol gene.
The hairy root is induced by _______________ for secondary metabolite/small molecules production.
Totipotency refers to the ability of an entire plant to be generated from a single, non-reproductive cell.
What pest almost destroyed the papaya industry in Hawaii?
Papaya ringspot virus
What enzyme is responsible for the rottening of tomato?
Scientists have developed a Bt cotton plant by using recombinant technology that allows it to____________.
Protect itself from larvae
What is the name of the selectable marker used in transgenic plant?
What step is not involved in the plant transient expression?
Plant tissue culture
Antisense technology refers to ____________________.
Selective blocks or silenced expression of a gene
The biolistic DNA delivery system refers to __________________.
Many crops have been made resistant to the herbicide, Round Up (glyphosate), by:
Introducing EPSPS, an enzyme that involves in amino acid biosynthesis
Which of the following statements is incorrect?
A plantibody is produced by a B cell
Which of the therapeutic enzyme is produced in carrot cell culture by Protalixs.
What step is involved in the Agrobacterium tumefaciens transformation?
T-DNA region is transferred to the plant cell during infection
Which of the following is not true of Agrobacterium tumefaciens?
It is a gram positive bacteria
Golden rice is rich in _______________________; it was first created by Swiss scientist Ingo Potrykus in 2000 to treat the people with vitamin A deficiency
What is plant biotechnology? How would you explain a transgenic plant to a friend?
Plant biotechnology means bioengineering plants and changing their genetic code to create better crops, and even medicine for humans. A transgenic plant is one in which a genetic code has been altered through bioengineering to improve the plant, for example Flavr Savr tomatoes has a gene encoded that codes for an antisense molecule that binds to the gene that causes ripening in a tomatoe and delays it. Thus making those tomatoes last longer before rotting.
Which promoter is always used for protein expression in plants?
What was the first genetically modified crop to be sold in supermarkets in the United States?
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