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Francis Scott Key saw Fort McHenry hold out during the night against a British attack. He wrote the poem "Star Spangled Banner" about the experience of seeing the U.S. flag still flying above the fort in the morning, and the poem was later set to the tune of an old English song and became the national anthem.
1804-1806 - Meriwether Lewis and William Clark were commissioned by Jefferson to map and explore the Louisiana Purchase region. Beginning at St. Louis, Missouri, the expedition travelled up the Missouri River to the Great Divide, and then down the Columbia River to the Pacific Ocean. It produced extensive maps of the area and recorded many scientific discoveries, greatly facilitating later settlement of the region and travel to the Pacific coast.
The Cherokee Indians were forced to leave their lands. They traveled from North Carolina and Georgia through Tennessee, Kentucky, Illinois, Missouri, and Arkansas-more than 800 miles (1,287 km)-to the Indian Territory. More than 4,000 Cherokees died of cold, disease, and lack of food during the 116-day journey.