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Endocrine Disorders: Basic Definition
Basic definitions of a broad and thorough (though certainly not exhaustive) list of endocrine disorders.
Occurs in adults: caused by a benign pituitary tumor (adenoma).
Occurs in children: caused by a benign pituitary tumor (adenoma).
Empty Sella Syndrome
May result in loss of pituitary functions: ceasing of menstrual periods, infertility, fatigue, and intolerance to stress/infection.
Milky discharge from the breasts of men or women who are not breastfeeding
Inhibited production of one or many of the following: GH, LH, FSH, TSH and ACTH
Feel weak, tired, and dizzy when standing up after sitting or lying down and may develop dark skin patches.
Congenital Adrenal Hyperplasia
Too much salt and water are lost in the urine, genital anamolies
The fatty covering (myelin sheath) on nerve fibers in the brain is lost, and the adrenal gland degenerates, leading to progressive neurological disability and death.
Hypokalemia, increased blood pH (alkalosis), hypertension, excess aldosterone
Obesity, increased fat in the neck and shoulder area, and thin fragile skin that bruises easily and heals slowly.
Diabetes Mellitus Type I
The body's pancreas does not produce enough insulin
Diabetes Mellitus Type II
Glucose isn't properly processed due to insulin insensitivity
Excess hair growth
Osteoporosis, osteomalacia, kidney stones
Spasms, tetany, seizures
Menstrual cramps severe enough to prevent participation in normal activities
Multiple Endocrine Neoplasia
Predispose people to develop benign tumors of the endocrine glands
Bone loss and weakness
Polycystic Ovary Syndrome
If untreated may lead to infertility, excessive hair growth, acne, obesity, diabetes, heart disease, high blood pressure, abnormal bleeding from the uterus, and cancer.
Caused by lack of iodine in diet
Autoantibody 'thyroid-stimulating immunoglobulin' (TSI) mimics the action of TSH on the thyroid
Autoimmune attack on thyroid causes it to become swollen and unable to synthesize sufficient hormone
Any condition in which the thyroid is overactive
Any condition in which the thyroid is underactive
Thyroid deficiency in newborns can lead to growth failure and permanent mental retardation
Low T3 Syndrome (Wilson's Syndrome)
Reduced thyroid function due to a failure to convert sufficient T4 to T3