NSC 330 Alpha 2 and Dopamine

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What is the Alpha 2 adrenergic agonist prototype?
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Terms in this set (17)
What is the Alpha 2 adrenergic agonist prototype?
Clonidine
Where are alpha 2 receptors located
in the brain
What is the Beta 1 adrenergic agonist prototype?
Dopamine
What system to Beta adrenergic agonist mimic.
sympathetic nervous system
What is the pharmacotherapeutic effect of dopamine?
treats hemodynamic imbalances present in shock and low doses are used to improve renal function
How is dopamine distributed in the body?
tissues
How is dopamine metabolized?
kidney, liver and plasma
How is dopamine excreted?
kidneys
What is the onset of dopamine and the duration?
5 minutes to onset and 10 minutes in duration
What are the pharmacodynamics of dopamine?
It acts on the Alpha 1 and Beta 1 receptors which increase cardiac output
What are the contraindications for Dopamine?tachyarrythmias and ventricular fibrillation and pheochromocytoma (tumor on adrenal glands)pheochromocytomaa benign tumor of the adrenal medulla that causes the gland to produce excess epinephrineWhat are the adverse effects of dopamine?ectopic beats, NV, tachycardia, angina, palpitations, hypotension and vasoconstrictionHow is dopamine administered?IVDo you use a pump or can you give dopamine as IV push?pumpWhen giving dopamine what do you monitor?The IV site for extravasation and disproportionate rise in diastolic pressureWhen is the treatement with dopamine considered successful?If BP stabilizes, urinary output and CO return to normal limits.