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10 terms

Furosemide (Lasix)

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Class
Loop diuretic
Action
Decreases preload by vasodilation effect in less than 5 minutes
Inhibits electrolyte reabsorption in the distal loop of henle, and promotes the excretion of sodium, potassium, hydrogen, magnesium, and chloride to decrease circulating blood volume by it's diuretic effect within 5-30 minutes
Indications/uses
Cardiogenic pulmonary edema
CHF
Contraindications
Anuria, Hypersensitivity, hypovolemia/dehydration, states of severe electrolyte depletions, known hypersensitivity to sulfonamides
Side effects
CNS: Dizziness, Headache, Tinnitus, Vertigo
Cardio: Arrhythmias, Hypotension
GI: Diarrhea, nausea, vomiting
Other: Hypovolemia, hypokalemia, hyponatremia, metabolic acidosis
Drug interactions
Digitalis toxicity may be potentiated due to potassium depletion, which can result from furosemide administration
Lithium toxicity may be potentiated due to sodium depletion
Preparations
20 mg/2 ml ampule/preload
40 mg/4 ml ampule/preload
100 mg/10 ml vial/preload
Adult dose
Not taking lasix: 40-80 mg
Taking lasix: 20-40 mg
May repeat p.r.n. to a maximum of 2 mg/kg. Do not exceed 20 mg/min
Pediatric dose
1 mg/kg slowly. May repeat p.r.n. to a maximum of 2 mg/kg
Note: Usually not given to pediatrics in prehospital setting
Route
IVP