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Pharm Ch33: Nifedipine (Adalat, Procardia XL)

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THERAPEUTIC

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Terms in this set (13)

antihypertensive

calcium channel blocker, dihydropyridine type

HTN, chronic stable or variant angina
decrease BP, decrease O2 demand, decrease afterload

MECHANISM OF ACTION

binds reversibly to closed-type calcium channels
decrease intracellular calcium avail for muscle contraction
decrease myocardial conduction