Varicose veins and venous leg ulcers b/c of increase back pressure on venous return. Heart size increases, HTN, Type 2 diabetes, Hyperglycemia, Gallstone formation, Rise in cholesterol and triglyceride levels--->CAD, Excessive weight on weight-bearing joints (hips and knees)-->osteoarthritis. Menstrual irregularities, infertility, endometrial CA, fatty liver infiltration. Life expectency shortened. Emotional and social problems-->discrimination, difficult to obtain job, social acceptance, and membership in organizations. Choice of clothing limited. Poor self-esteem and body image.