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Hemolytic anemia (acquired hemolytic anemia) ❤️

Terms in this set (23)

Condition caused by the distraction or the Hemolysis of RBCs at the rate that exceeds production
What is hemolytic anemia
Hereditary, results from defects in red blood cells themselves
What is intrinsic hemolytic anemia
Caused by external factors red blood cells are normal
What is extrinsic hemolytic anemia
Spleen
What organ is a primary side of destruction of red blood cells
Jaundice, spleen and liver enlargement
Clinical manifestations of hemolytic anemia
Increased destruction of red blood cells caused by elevation in Bilirubin levels
In hemolytic anemia Jaundice is due to
Hyperactivity
Spleen and liver enlarge due to
Maintaining renal function when red blood cells or hemolyzed hemoglobin is released and filtered by the kidneys the cumulation of hemoglobin molecules can obstruct Renal tubules and lead to acute tubular necrosis
What is the major focus of treatment in hemolytic anemia
He will lyses of red blood cells from extrinsic factor
What is acquired hemolytic anemia
Macro angiopathic which is physical destruction, microangiopathic distraction, antibody reactions, infectious agents
For categories of acquired hemolytic anemia
Results from exertion of extreme force on cells causes disruption in the red blood cell membrane
What is macro angiopathic
Hemodialysis, bypass and prosthetic heart valves force is needed to push through the abnormal vessels which damages it RBCs by burning or Irradiating them
What can cause macro angiopathic hemolytic anemia
Fragmentation of red blood cells when they try to pass by abnormal arterial or venous microcirculation red blood cells are shared when they try to pass by excessive platelet aggregation
What is microangiopathic distraction
Thrombotic thrombocytopenic you and disseminated intravascular coagulation
Microangiopathic distraction is seen in
Distraction of red blood cells by antigen antibody reaction can be isoimmune or autoimmune
What is an antibody reaction in hemolytic anemia
Isoimmune reaction
What occurs when antibodies develop against antigens from another person of the same species such as blood transfusion
Autoimmune reaction
Individuals develop antibodies against their own red blood cells maybe idiopathic or secondary to autoimmune disease is such as lupus, leukemia or medications
Invasion of red blood so destroying its contents like malaria, releasing hemolytic substances, toxins that involve chemicals such as arsenic, lead, copper, bee stings or spider bites
Infectious agents and toxins can cause destruction of red blood cells by
Aggressive hydration and electrolyte replacement to reduce risk of kidney injury caused by red blood cell lysis clogging Renal tubules
What nursing care should be ready to institute in case of emergency
Corticosteroids and blood products
What can be administered in acquired hemolytic anemia
Splenectomy
What surgical procedure might be done in acquired hemolytic anemia
Immunosuppressive agents
What can be used to suppress red blood cell destruction
Folate
What might need to be replaced in chronic hemolytic anemia
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