A: Aspirin Toxicity, and
C: Carbohydrate not metabolizes and cause lactic acid, and
I: Insufficient kidney function and not excreting H+, and
D: Diarrhea, which lose Alkaline fluid (HCO3-), and
O: Ostomy drainage such as ileostomy, and
T: as fisTula, and fluid movement, and
I: Intake of FAT diet high in Keton and low in HCO3-, and
C: Carbonic Anhydric Inhibitor, which is Diamox. It does not absorb HCO3-.