How can we help?

You can also find more resources in our Help Center.

8 terms

Synovial Fluid Crystals

Monosodium urate (MSU) crystals
Intracellular, approximate diameter of neutrophil
Strongly negatively birefringent (yellow)
Calcium pyrophosphate dihydrate (CPPD) crystals
Weakly positively birefringent (blue)
Chondrocalcinoisis (x-ray)
Calcium basic phosphate (CBP) crystals
Small - only identified by electron microscopy
Not birefringent
Clumps of crystals (shiny coins) under LM
Alizarin red stain to detect calcium-containing crystals
Acute inflammatory arthritis (young people)
Milwaukee shoulder (older people)
Calcium oxalate crystals
bipyramidal and envelope shaped
Stain with alizarin red
Primary oxaluria (autosomal recessive)
Kidney failure on hemodialysis
Cholesterol crystals
Very large
Flat and rectangular shaped
Notched corners
Varying birefringence
Rheumatoid arthritis
Corticosteroid crystals
Strongly variably birefringent
Polymorphic clumps, rods, or rhomboids
May cause joint pain for several hours
Talc crystals
Originate from latex gloves during arthrocentesis
Strongly birefringent
Maltese cross pattern
Free fat
oil-red-O - stains droplets red
osmic acid - stains droplets black
Most likely result of trauma (intra-articular fracture)

Flickr Creative Commons Images

Some images used in this set are licensed under the Creative Commons through
Click to see the original works with their full license.