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Biochem Quiz 5 to Mini dos
Terms in this set (48)
What are the aliphatic amino acids??
Glycine, valine, alanine, leucine, isoleucine
Are aliphatics hydrophobic?
What are the aromatic AAs?
Tyrosine, phenylalanine, tryptophan
Which AA absorbs UV light the best?
What is the Beer lambert law?
A = Elc
What are the basic amino acids?
Lysine, arginine, histadine
Are basic amino acids hydrophobic?
What are the sulfur amino acids?
Cystein and methionine
Are sulfur amino acids hydrophobic?
What is the henderson hasselbach equation?
pH = pKa + log (A/HA)
If you pH is less than your pka1 than your carboxyl group is...
If your pH is greater than your pka 1 than your carboxyl is...
What protein structure has the amino acid residues in peptide chains?
What structure only involves H bonding?
What form of protein structure is a biologically active protein?
What causes a 67 fold increase in the O2 carrying capacity of the blood
What are the two histadines that the globin structure is positioned between?
F8 and E7
Which histadine can bind?
What does E7 do?
Protects Fe2+ from turning into Fe3+
What is the change in affinity when O2 binds to Hb?
What is the mech for cooperatively?
Bond shifts between relaxed and tense state
What bonds are in the T state?
Tryptophan to aspartate
What bonds are occur in R state?
Aspartate with Asparagine
What is the disorder associated wit Hb where proximal histadines are replaced by Tyrosine?
Transprts thyroxine and T3, levels decrease in inflammation
Combines with pre albumin, transports vitamin A
Is a serine protease, inhibits elastase
Inactivates progesterone, increases in inflammation
Alpha 1 - acid glycoprotein
Major plasma protein of fetus, low concentration in downs syndrome
alpha 1 -Feto protein
Functions in inflammation and coagulation, increases in estrogen therapy
Alpha 2 macroglobulin
Transports free HB to triculoendothelial cells, Hb can precipitate in kidney = damage
Transport protein that binds free heme and takes Heme to liver and converts it to bilirubin
Transports copper, leads to WILSONS and MENKES
Fxns to transport iron, takes iron to bone marrow
Small protein that passes through glomerulus, used to assess renal tubule function
Complement activation, binds and removes toxins, used to detect infections, SLE, and kidney transplant rejections
Reactive C protein
M spike on EP
Small m protein band but no symptoms
M spike that is IGM!!
No M spike, decrease in albumin, increase in gamma region
Lots of protein bands on Gel Compared to normal
Renal kidney impairment
What is the allosteric regulator for CPS1?
N acetyl glutamate
What enzyme is responsible for Phenylketonuria?
What urine deficiency is caused by build up of cysteine?
What is due to a deficiency of BDKDC?
Maple syrup urine disorder
What amino acids cause SOTOLON?
Isoleucine, leucine, valine
Black urine disease:
Urine disease caused by deficiency of enzyme that transfers sulfer to homocyteine to serene:
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