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antineoplastic pharm
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Terms in this set (46)
cell-cycle nonspecific drugs
alkalating, antibiotic
M phase action
vinca alkaloid
G2 phase action
bleomycin
S-->G2 phase action
etoposide
S phase action
antimetabolite, topotecan
Mechlorethamine
nitrogen mustard (binds N7 of guanine in DNA, crosslinking, strand breaks)
Cyclophosphamide
nitrogen mustard (crosslinks DNA and RNA)
Carmustine
nitrosurea (alkylate DNA, strand breaks)
Lomustine
nitrosurea (alkylate DNA, strand breaks)
busulfan
alkyl sulfonate (crosslink DNA)
dacarbazine
DNA/RNA synthesis inhibitor
procarbazine
H2O2 DNA/RNA synthesis inhibitor
Cisplatin
platinum (attach muceophilic DNA sites, crosslinking)
Give with MESNA
cyclophosphamide
brain tumors
nitrosurea
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