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Introduction to Pharmacology (exam review 3) Asperheim-Favaro

Chapter 18- 19-20-21
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A diet that would be recommended for a patient undergoing chemotherapy would include?
High protein, low saturated fat foods
A malignancy arising from epithelial cells is known as
Carcinoma
A patient asks the doctor to prescribe epoetin (Procrit) for her tiredness related to having cancer. She has seen an advertisement on television promising her that this will increase her energy level. What must be explained to the patient about this medication?
It is for the treatment of chronic anemia and will not result in increasing energy related to other causes
Acute lymphocytic leukemia of childhood has been noted to go into remission as a result of treatment with?
Corticosteroid agents
An autoimmune condition in which erythrocytes are destroyed by antibodies causing the patient to experience fatigue chills fever dyspnea and jaundice is:
autoimmune hemolytic anemia
Antimetabolite agents act primarily by which of the following actions..
mimicking purine folic acid; and pyrimidine in the cell
Antineoplastic drugs are most likely to be toxic to which of the following
most rapidly dividing healthy tissues
Autoimmune disease occur only in the blood and lymphatic systems.
false
Alkylating agents are a type of genotoxic drug because of which of the following actions
damage to the DNA structure leading to cell death
Adrenocorticotropic hormone (ACTH) has what effect on the body?
stimulation of hydro-cortisone secretion
Which of the following are types of antineoplastic drugs?
antimetabolite agents
Because of its inhibition of the factors that stimulate T-lymphocyte growth, cyclosporine is used to:
Used to prevent rejection of organ and bone narrow transplant
Because of the drugs' action to suppress the body's inflammatory response, patients on long-term adrenocorticoid agents are at risk for the unrecognized advance of?
Tuberculosis and perforated ulcer
Because of their selective estrogen-agonist properties, selective estrogen receptor modulated aromatase inhibitors (SERMs) can be used to:
prevent or treat diseases caused by estrogen deficiency
Before having a surgical correction for prostatic hypertrophy, a patient might take a course of what drugs?
Uroxatral -avodart-proscar
Bleomycin (Blenoxane) differs from most antineoplastic agents in what ways?
the drug has a low incidence of bone marrow toxicity
During treatment with doxorubicin (Adriamycin), the patient should be monitored for what; because of the possibility of serious side effects?
electrocardiogram changes
For what would a patient with AIDS be prescribed megestrol (Megace)?
Who have poor appetite
Goserelin acetate (Zoladex) are used to treat what?
prostate cancer, breast cancer and endometriosis
Hib vaccine provides immunity against which pathogen?
Haemophilus influenza; infections in infants and young children
Hypothyroidism tends to occur in geographic regions that are deficient in?
iodine
Immunity provided by the mumps-measles-rubella (MMR) vaccine is less than optimal if administered before what age?
12 months of age
In addition to its role as an antineoplastic drug, cyclophosphamide (Cytoxan) is also used to treat?
Autoimmune disorders, such as systemic lupus erythematosus, rheumatoid arthritis, and nephrotic syndrome, and to prevent organ transplant rejection.
In addition to its use as an antineoplastic medication, lomustine (CCNU) is also used in the treatment of what other condition?
Mycosis fungoides and psoriasis
In addition to treatment of prostate cancer, leuprolide (Lupron) is also used to treat what?
Central precocious puberty
Interferon is an example of what category of antineoplastic agents?
alkalating agents
Live influenza virus vaccine (FluMist) differs from the vaccines for polio and hepatitis in which of the following ways?
Is administered into each nostril by sprayer
Multiple sclerosis (MS) patients often benefit from treatment with forms of interferon beta because of what rationale?
Because interferons are proteins that posses complex antiviral, antineoplastic, and immunomodulating activities.
Oxybutynin (Ditropan) is given for the treatment of what?
Bladder spam.It may be used for day and night wetting
Phenazopyridine (Pyridium) is prescribed for urinary tract infections to produce?
analgesic effect on the urinary tract mucosa
Regulating hormones that affect all the other endocrine glands in the body are secreted in which locations?
Anterior lobe of the pituitary gland
Teriparatide (Forteo), a medication used to treat osteoporosis, is derived from which source?
Fragment of human parathyroid hormone (recombinant DNA origen)
The goal of insulin pump therapy is to do?
Deliver both basal doses and boluses to stimulate normal beta cell function
The hormone that induces favorable conditions for the growth and development of the fetus is
Progesterone
The patient receiving chemotherapy should be instructed in what regimens for oral hygiene?
FREQUENT, GENTLE CLEANSING OF THE MOUTH
The poliovirus vaccine (IPOL) can be administered by which route
IM or subcutaneously.
To manage gastrointestinal symptoms during treatment with nitrofurantoin (Macrodantin), what would be recommended for the patient to take with each dose of the medication?
food and milk
Under what conditions might immunizations be withheld for an interval?
When receiving corticosteroids or antineoplastic agents, or when family members are immnologically compromised.
Water loss that is difficult to detect and measure is called:
TERMED INSENSIBLE PERSPIRATION or insensible loss
What antibody preparation is used to desensitize Rh-negative mothers after delivery of an Rh-positive infant?
Rho (D) IMMUNE HUMAN GLOBULIN (RhoGAM)
What antineoplastic drugs might be administered orally, intramuscularly, intravenously, or as an intracavitary infusion?
Cyclophosphamide (Cytoxan)
What are types of antineoplastic drugs?
Drug used to treat cancer
What are used to suppress the thyroid gland before surgery?
Tyroid preparation 60 mg.- levothynoxine - syntroid
What disorders may occur if the thyroid fails to function properly during the formative years of a child's development?
cretinism
What drug for treatment of nausea and vomiting associated with cancer chemotherapy is available in transdermal patches?
Granisetron (kytril)
What drugs are given for the treatment of benign prostatic hypertrophy (BPH)?
Avodart- uroxatral- finasteride (proscar) Alfuzosin Hcl, Dutasteride, Silodosin, Tamsulosin
What foods could be recommended to a patient who is taking thiazide diuretics?
Potassium supplements potatoes, orange, bananas.
What is a loop diuretic agent?
Furosemide (Lasix) act throughout the collecting tubules of the nephron, particularly on the ascending limb of the loop of Henle, to prevent the reabsorption of - and hence cause the excretion of- sodium and chloride.
What is necessary for oral hypoglycemic agents to be effective in managing diabetes?
For maintain the blood glucose level.
What is the drug used to immunize young adults against the causative agent of cervical cancer?
Human papillomavirus vaccine (Gardasil)
What laboratory tests should be done regularly with patients on diuretic therapy?
Fluid /electrolyte
What may accompany the use of hormone replacement therapy for women in menopause?
estrogen replacement therapy
What may help the chemotherapy patient cope with the nausea and vomiting that often accompany intravenous infusion treatment?
sedation and antiemetic medication before treatment
What might be used topically for the treatment of actinic keratoses?
Fluorouracil (5-FU)
What urinary agents commonly causes the urine to turn red, which should be explained to the patient before starting treatment with the drug?
Phenazopyrine Hcl (Pyridium)
With proper therapy the prognosis for children with juvenile rheumatoid arthritis JRA is
generally good
A sytemic usually progressive inflammatory disease primarily affecting the spinal colum
ankilosing spondilitis
Which of the following may accompany the use of hormone replacement therapy for women in menopause?
breast cancer and cardiovascular complications
Which of the following is necessary for oral hypoglysemic agents to be effective in managing diabetes
release of residual insulin by the pancreas
Which of the following enzimes derived from Escherichia coli is used in the treatment of acute lymphocytic leukemia
asparaginase (elspar)
Which of the following are used to suppress the tyroid gland before surgery?
methimazole and propylthiouracil
Which of the following are true about raloxifene hydrochloride (evista)
it has lower incidence of breast cancer as a side effect than other similar medications. It is taken by moth daily.
When the immune system reacts appropriately to an antigen and homeostais is maintained it is termed
immunocompetence
What is dactinomycin (Actinomycin D) used to treat?
wilms tumor of the kidney
Tolerance to self antigens is believed to commence during fetal life?
True
There are not cures for connective tissue diseases; and treatment is only palliative
True
The inflammatory disease of the CNS that attacks the myelin sheath is
multiple sclerosis
The group of diseases that occur when antibodies develop and begin to destroy the bodys own cells is
autoimmune diseases
The patient with a platelet deficiency and the inability of blood to clot has
idipathic thrombocytopenic anemia
The primary treatment of rheumatoid is
a) reduction of inflammation and pain b) preservation of joint function c) prevention of joint deformity. All of the above
The disease that begins with inflammation and edema of the synovial membranes surrounding the joint is
rheumatoid arthritis
The acquired immunity that results when a person has a disease is
active
Pyridostigmine bromide (Mestinon) is the drug of choice for treatment of
A chronic progressive, neuromuscular disease that is characterized by the extreme muscular weakness , generally appearing first in the face an progressive fatige is
myasthenia gravis
Immunoglobulins that provide the ability to recognize foreing organisms stimulating the antigen antibody reaction are called
cells
Decreased gastric production of hydrochloric acid and the resulting shortage of the intrinsic factor cause
pernicious anemia
Autoimmune diseases occur when autoantibodies develop and begin to destroy the bodys own cells
true
A chronic progressive sytemic autoimmune disease of the skin that is characterized by hardening and shrinking of the skin is
systemic scleroderma
What is the drug used to immunize young adults against the causative agent of cervical cancer?
HPV Vaccine (Gardasil)
For what would a patient with AIDS be prescribed megestrol (Megace)?
Anorexia and weight loss
Opportunistic infections can emerge as a result of deficiencies of the immune system
true
A history of repeated, chronic infections, which includes sinopulmonary symptoms e.g. sinus tenderness, cough, fever, runny nose, abnormal sputum, dyspnea, along with gastrointestinal GI symptoms, diarrhea, abdominal pain, weigh loss, is usually indicative of
common variable immunodeficiency disease (CVID)
The most common form of immunodeficiency is
selective immunoglobulin A deficiency disease
Symptoms of fever,joint pain, malaise, weight loss, and the characteristic butterfly rash are indication of
Systemic lupus erythematosus