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Oxygen Transport

Terms in this set (35)

Normal range of PAO2- Pao2 for healthy young adults breathing room air.
5 to 10 mm Hg
what is true about Pulmonary blood flow in the upright lung
The bases receive about 20 times more blood flow than the apexes.
Measurements used to find patients alveolar ventilation
PaCO2
Breathing room air, a normal PAO2 - PaO2 of 5 to 10 mm hg exists because....
Anatomical shunts in the pulmonary and cardiac circulation
Regional differences in pulmonary ventilation and blood flow
Chronic hypoxemia causes a primary and sustained elevation in intracellular 2,3 DPG concentrations. This does what?
Increases the availability of O2 to the tissues
Hypoxemia can be caused by which of the following?
Diffusion impairment
Alveolar hypoventilation
v/q mismatch
intrapulmonary shunting
Vales corresponds most closely to the normal PO2 and PCO2 in the mixed venous blood returning to the lungs from the right side of the heard
PO2= 40 mmHg ; PCO2= 46 mmHG
A patient has a P50 value of29 mm Hg. What does this mean...
A decreased affinity of Hb for O2
at PaO2 of 60 mm Hg, what is the approximate saturation of Hb with O2
90%
the amount of O2 delivered to the tissues depends on which of the following
CaO2, Cardiac output (Qt)
what is a normal range of PAO2- PaO2 breathing 100% O2
25 to 65 mmHg
what happens when the temperature of the blood rises?
The Hb saturation for a given PO2 falls
The HbO2 curve shifts to the right
What is a minimally acceptable PAO2 - PaO2 breathing 100% O2
< 350 mm Hg
What is the highest PAO2 one could expect to observe in an individual breathing room air at sea leave
90 to 100 mm Hg
How is the vast majority of O2 carried in the blood
Chemically combined with Hb
Hypoxia is best defined as a condition in which what occurs
tissue O2 delivery is inadequate to meet cellular needs
Tissue oxygenation is considered inadequate if the SvO2 falls below what leavel
65%
Given the following bl0od parameters compute the total O2 content (dissolved + HbO2) of blood in ml/dl : Hb= 18; PO2 = 40; SO2= 73%
17.7 ml/dl
(18 x .73 x 1.34)+(0.003 x 40)
17.607+0.12=17.7
tissue oxygenation is considered inadequate if the PvO2 falls below what level?
30 to 35 mm Hg
in order to assess the events occuing at the tissue level, especially tissue oxygenation, what parameter whould you sample and measure?
systemic venous blood
on what does the movement of gases between the lungs and the body tiddues mailny depend?
gaseous diffusion
When will erythrocyte concentrations on 2,3 DPG be decreased
banked blood
What conditions must exist for gas to move between the alveolus and pulmonary capillary?
A difference in partial pressures
given the following blood parameters, compute the total O2 content ( dissolved + Hbo2) of the blood in ml/dl: Hb= 16; PO2= 625; SO2 =100%
(16 x.100 x 1.34)+ (0.003 x 625)
(16x1.34)+(1.875)
21.44+1.875=23.3 ml/dl
O2 exchange at the lungs is considered adequate if the PaO2 can be maintained in what range?
80 to 100 mm Hg
All of the following can increase the affinity of Hb for O2 except which one?
Increased temperature***
Decreased 2,3 DPG
Decreased PCO2
Increased pH
O2 exchange at the lung is considered adequate if the arterial hemoglobin (Hb) saturation (SaO2) can be maintained above what level?
90%
Compared to normal levels a shift in the HbO2 curve to the right has which of the following effects
the Hb saturation for a given PO2 falls
the affinity of Hb for O2 decreased
what is the primary determinant of the PAO2
POs in the inspired gas
Breathing 100% O2 a pt has a PAO2 of 60mm Hg based on this info what may you conclude?
the Pt has acceptable oxygenation
In evaluation the oxygenation status of a patient just placed on ventilatory support with an FiO2 of 1.0 you compute a PAO2 - PaO2 of 300 mmHg. what is pt Qs/Qt
300-65=235
25%
10 mm Hg diff= 1%
with all else being equal under which of the following conditions will the CvO2 of a pt blood decrease
when tissue oxygen uptake (VO2) increases
when CaO2 falls
When Qt decreases
what is the approximate normal CaO2- CvO2 in a healthy adult at rest?
5 ml/dl
A pt has a whole body oxygen consumption of 320 ml/ min and a measured CaO2- CvOe of 8 ml/dl. What is the cardia output?
4.0 L/min
The affinity of CO the Hb is approximately how many times greater than that of O2?
200 to 200 times greater
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