NARM study: MIA module 4, Prenatal Testing and Risk Screening
Terms in this set (28)
Varicella in pregnancy --> maternal complications:
Varicella in pregnancy --> fetal complications:
congenital varicella syndrome:
eye and CNS damage
Varicella in late pregnancy (6d before labor through 2d PP) --> neonatal complications:
neonatal infection s passive immunity -->
5% mortality rate
Untreated chlamydia -->
vertical transmission at birth
untreated gonorrhea -->
ascending infection during PP
untreated syphillis -->
40% risk: abortion, stillbirth, perinatal death
40% risk: congenital syphillis, lesions in internal organs and long bones, death
active HSV outbreak @birth -->
transmission with ROM
50% rate transmission @ birth
risk of transmission after birth
neonatal infection --> 60% mortality
genital warts (HSV/condylomata acuminata) -->
excessive bleeding if torn
neonatal laryngeal pappilomatosis
rubella contracted in 1st trimester -->
52% risk of CRS:
growth retardation, CHD, CNS defects, cranial defects
cytamegalovirus in pregnancy -->
fetal defects of vision and hearing, mental retardation
toxoplasmosis- most critical period?
late 1st trimester
toxoplasmosis in pregnancy -->
cranial and mental defects
Parvovirus B19-- most critical period? -->
Parvo in pregnancy -->
20-30% transfer rate
fetal anemia, hydrops
severe asthma as risk factor:
may not go into labor if on meds (they act as tocolytic)
Maternal serum AFP screening test- for?
risk of open NTD or Down syndrome
high AFP= increased risk of NTD
low AFP= increased risk of DS
Triple Screen rate of detection of DS in women >35y?
Triple screen tests what?
MsAFP, hCG, unconjugated estriol
ABO incompatibility: most maternal anitbodies are what type?
IgM-- too large to cross placenta
ABO incompatibility: antigens on what fetal cells?
all tissue cells, not just RBCs
50% ABO incompatibility rates are with what types?
Maternal O and fetal A
Most severe ABO incompatibility in which types?
Maternal O and fetal B
ABO incompatibility does not usually cause severe complications; rather -->
free from germs
test for genetic disorders: needle inserted through abdominal wall and uterine wall into uterus to collect amniotic fluid; increased risk of fetal injury or miscarriage