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Action: Bactericidal, Alter DNA of bacteria, causing death by interfering with bacterial enzymes DNA. Does not affect human DNA. Ciprofloxacin (Cipro), enoxacin (Penetrex), Levofloxacin (Levaquin) (one day dosing), norfloxacin (Noroxin), moxifloxacin (Avelox). Therapeutic Uses: Lower respiratory tract infections / pneumonia. Sinusitis Gastrointestinal tract/Infectious diarrhea. Eye infections Serious Urinary tract infections Sexually transmitted diseases Skin, bone, joint and soft tissue infections. Implications: Should be taken with at least 3 L of fluid per day, unless otherwise specified. May be taken with food. Do not take concurrently with antacids, ferrous sulfate, multivitamins or mineral supplements since they contain CA, MG, Iron, or Zinc ions and reduces absorption by 90%. If taken with Warfarin it may increase anticoagulant effects and result in bleeding. Assess: Abdomen for bowel sounds, texture and patterns. Neuromuscular fx: due to a potential for dizziness, headaches and visual changes; renal and liver function tests: (BUN, Creatinine and Liver enzymes), as well out urinary output. blood glucose levels. (The Quinolones increase insulin release from pancreatic islet cells).Adverse: CNS: H/A, dizziness, fatigue, depression, seizures, and sleep disturbance. Cardiac: May involve prolongation of the QT interval. Seen more so if pt. is taking cardiac drugs in conjunction like Amiodarone (antiarrhythmic agent, medication used for irregular heart beat). GI: N/V, diarrhea, thrush, lab shows an increase in Liver enzymes Superinfections and anaphylaxis may occur. Report difficulty when walking, pain in feet or legs immediately.