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EPA 2 - Genital System
Terms in this set (55)
1st six weeks of development where male and female structures are the same.
After six weeks where genitalia are either male or female.
Leads to urogenital system which consists of the urogenital ridge.
Ridge containing two structures: the nephrogenic ridge and the gonadal ridge.
Primordial Germ Cells
Originate in endoderm of yolk sac near allantois and migrate to intermediate mesoderm.
Genital Ridge Mesenchyme
Derives from intermediate mesoderm
Mesothelium of genital ridge which forms sex cords.
Intiatied testes development and can be found on short arm of Y chromosome with testes determining factor. Medulla grows and cortex regresses.
Form primitive seminiferous tubules. Secrete androgen binding protein and anti mullerian hormone.
Primitive Seminiferous Tubules
Include Sertoli and primordial germ cells.
From the genital ridge mesenchyme. Involved in testosterone production in week 8.
Dense layer of fibrous connective tissue which separated the sex cords from the mesodermal epithelium.
Caused by lack of SRY gene and lack of TDF, medulla regresses ad cortex grows in to ovary.
Secondary sex cords (cortical cords) develop in to cell clusters of these cells that form from primordial germ cells.
In cortical cords, from mesodermal epithelial cells.
Mesonephric Duct Wolffian
Attached to mesonephric tubule. Extends from mesonephros to urogenital sinus.
Paramesonephric Duct Mullerian
lateral to mesonephric duct with cranial ends open to peritoneal cavity.
Causes mesonephric ducts to differentiate in to epididymis, vas deferens, seminal vesicle, and ejaculatory duct.
Anti Mullerian Hormone
Produced by the Sertoli cells and causes paramesonephric ducts to regress and turn in to appendix testes.
Efferent Ductules of Testes
Formed from mesonephric tubules.
Gonadal Hormone Secretion
Is not necessary for female gonadal development but is necessary for males.
Ducts of Epoophoron
Formed from Mesonephric ducts
Epoophoron and Paroophoron
Formed from mesonephric tubules
Female Genital Tract
Formed from paramesonephric ducts. The cranial ends do not fuse leading to the uterine tubes and the caudal ends fuse forming the uterovaginal primordium
Is the caudal fused end of the paramesonephric ducts which forms the uterus and superior vagina.
Develops from proliferation of endoderm of urogenital sinus when paramesonephric ducts terminate. Canalizes by the 5th month.
Mesenchyme around cloacal membrane proliferated to form these raised elevation.
Formed from the elongation of the genital tubercle cranial to the cloacal membrane
Lateral to Cloacal Folds
Formation of urogenital and labioscrotal swellings
Divides cloacal membrane in to anterior urogenital membrane and posterior anal membrane.
Released from testes and causes male differentiation
Phallus in males elongated to form glans and dorsal wall.
Body of Penis
Formed from fusion of the urogenital folds in males.
Formed from endoderm of the urethral groove.
Formed from ingrowth of ectodermal cells in the glans.
Formed from fusion of the labioscrotal swellings in males.
Formed from fusion of phallus in females.
Formed from lack of fusion of urogenital folds in females
Formed from lack of fusion of labioscrotal swellings in females.
Vestibule of vagina
Formed from disruption of urogenital membrane in females.
Occurs in posterior abdominal wall external to peritoneum. Attached caudally by gubernaculum to labioscrotal swellings.
Formed from degeneration of gubernaculum in males.
Outpouching of abdominal peritoneum that carries muscular and fascial extensions of anterior abdominal wall
Formed from degeneration of the processus vaginalis
Internal Spermatic Fascia
Formed from descent of the transversalis fascia
Formed from descent of Internal Abdominal Oblique muscle.
External Spermatic Fascia
Formed from descent of External Abdominal Oblique muscle.
Formed from cranial degeneration of gubernaculum in females.
Formed from caudal degeneration of gubernaculum in females.
Presence of both testicular and ovarian tissue with ambiguous external genitalia
Gonad of one sex but external genitalia of another. Gonads are gender determining.
Overproduction of androgens with low cortisol and high ACTH. Can masculinize female genitalia or precocious puberty in males.
Androgen Insensitivity Syndrome
Testes secrete androgen but defect in receptors lead to testes with female external genitalia. Not diagnosed until puberty.
Urogenital folds do not fuse properly and leads to abnormal openings of urethra on ventral side of penis.
Androgen deficiency causes testes to remain undescended.
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