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deciding what is normal

Terms in this set (11)

packed cell volume
percentage of circulating blood that is red cells - haematocrit
mean cell volume
packed cell volume / RBC
(fl)
mean cell haemoglobin
Hb / RBC
(pg)
average amount of haem in a given volume of blood divided by number of red cells
mean cell haem concentration
Hb / PCV
(g/l)
average amount of haem divided by proportion of sample represented by red cells
steps to interpreting blood count (WITCHES HAVE MANY POWERS)
WBC and differential - is there leucocytosis/leucopenia and which line is abnormal
Hb - is there anaema
MCV - are the cells large or small - clues in clinical history
Platelet count - is there thrombocytosis/cytopenia
polycythaemia
too many cells - specifically refers to red cells
what would incraese in polycythaemia
Hb, RBC, PCV/Hct
what is pseudopolycythaemia
decreased plasma volume resulting in higher Hb, RBC, PCV/Hct
what is true polycythaemia
polycythaemia resulting from increase in number of circulating red cells
intrinsic bone marrow problem is called polycytheamia vera
what causes polycythaemia (5)
blood doping
medical negligence (transfusing more than once...)
high levels of erythropoietin (appropriate/not)
tumour secreting erythropoietin
abnormal function of the bone marrow - polycythaemia vera is intrinsic bone marrow disorder
what is polycythaemia vera
a myeloproliferative neoplasm (cancer starting in bone, resulting in over production of RBCs)
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