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13 terms

Thyroid Pharmacology

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Levothyroxine sodium
This drug is simply synthetic T4
Liothyronine
This drug is simply synthetic T3
L-thyroxine
This drug is preferable for the long-term treatment of hypothyroidism, because of its longer half-life
100
This is the average replacement dose (in ug) of L-thyroxine for hypothyroidism
thionamides
This class of drugs is used in the medium to long-term treatment of hyperthyroidism
propylthiouracil
This thionamide drug has a 2 h half-life and is less potent than methimazole
methimazole
This thionamide drug has a 12 h half-life and is more potent than propylthiouracil
iodination
Thionamide drugs work by inhibiting this from occuring to lumenal thyroglobulin
iodide salts
These drugs are effective for rapid relief of acute thyrotoxicosis (thyroid storms)
radioactive sodium iodide
This drug is used for the definitive medical treatment of hyperthyroidism
propranolol
This beta-blocker drug is an adjuvant therapy for symptom control of hyperthyroidism
calcium channel blockers
These drugs relieve the tachycardia of hyperthyroidism
dexamethasone
This glucocorticoid inhibits peripheral T4 to T3 conversion