1. Immediate response (acute phase response)
Stress or inflammation caused by infection, injury or surgical trauma causes selective increase in haptoglobins in alpha2 mobility band.
2. Increase of: haptoglobin, alpha-2 macroglobulin, ceruloplasmin, C-reactive protein, complement factors, certain blood clotting factors
3. Decrease of: albumin, antithrombin, transcortin