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ATI Infection Pharmacology
Terms in this set (93)
Antibacterial antibiotics that inhibit protein synthesis are?
Tetracycline class and uses
Antibacterial antibiotic that inhibits protein synthesis. Overused. First choice for chlamydia and mycoplasmal infections. Acne drug. Bacteriostactic
Tetracycline prototype and other drugs
Prototype is tetracycline
Other drugs: doxycycline (vibramycin), minocycline (Minocin).
Tetracycline side effects
GI symptoms, liver toxicity, suprainfections, photosensitivity, can discolor teeth in infant, children and women shouldn't take.
Mouth pain, difficulty chewing and swallowing (oral infection), vaginal yeast infection, watery or bloody stools (pseudomembranous colitis)
Tetracycline patient instructions/interventions
Take with nondairy food if GI upset occurs, report pregnancy, avoid giving to infants and children, report signs of liver damage (jaundice, abdominal pain, fatigue), wear protective clothing from sun, keep drug away from light
C: women who are pregnant, children less than 8, allergic,exposure to ultraviolet light, serious renal or liver failure
P: history of allergies (hay fever), liver or kidney disorder, myasthenia gravis
Calcium containing foods, anacids with calcium, magnesium and aluminum thry inactivate it, (antidiarrheals with kaolin, dairy products, iron and zinc decrease absorption), tetracycline decrease oral contraceptives
Macrolides class is
Antibacterial antibiotic that inhibits protein synthesis. It's bacteriostactic.
Macrolides prototype/other drugs
Other drugs: azithromycin (Zithromax)
First line treatment of legionnaires disease, whooping cough, acute diphtheria, treats common infections of patients have a penicillin allergy
Macrolides side/adverse effects
GI probs, cardiac symptoms, ototoxicity, suprainfections (pseudomembranous colitis, candidiasis)
Nausea, vomiting, abdominal pain, and diarrhea
Ototoxicity will cause
Hearing loss, vertigo, tinnitus
Macrolides interventions/patient instructions
Monitor for: GI, other drugs patient is taking, ototoxicity, suprainfections, take with food, report bloody and watery stools, mouth pain or vaginal discharge, heart dysrhythmias
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