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Medication management in acute kidney injury
Terms in this set (5)
Which of the following drugs/drug classes do NOT need review (consideration of dose adjustment or temporary cessation) in acute renal failure:
Diuretics, NSAIDs, ACEI, gentamycin, vancomycin, piperacillin-tazobactam, PPIs, trimethoprim, metformin, enoxaparin, opioids, quetiapine,
Which opioid analgesics are most appropriate in renal failure?
Fentanyl and oxycodone the most likely ones interns are most likely to prescribe
(tapentadol, hydromorphone less frequently used)
What VTE prophylaxis should you consider in AKI?
Renally adjusted enoxaparin (20mg/day) if CrCl<30
- Consider monitoring the anti-Xa level
Use heparin in end stage renal failure
What simple analgesia is NOT appropriate in patients with AKI?
What combination of medications, known as the "triple whammy", increases the risk of AKI
NSAIDs (afferent arteriole constriction)
ACEI (efferent arteriole dilatation)
Diuretics (reduced plasma volume)
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ACE inhibitors and ARBs