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Terms in this set (10)
Atypical lymphocytes. IgM to VCA. Heterophile antibodies.
Serology. Yeast @37 mold @25, thin walled oval. Aerial mycelial growth w/macroconidia. Yeast grow intracellularly in inactivated alveolar macrophages. cytokines cause fatigue/weight loss.
Blastomycosis case #18
Serology. Multiple nodular lesions on CXR. Mold at 25, yeast(infectious) at 37. Large yeast form w/broad based budding. Endemic to southeast. Suppurative and granulamatous inflammation. Lymph spread to other organs.
Coccidioidomycosis case #19
Serology. Mold in soil->arthroconidia in air->thick-walled non-budding spherules->endospores. California. Chronic granulomatous inflammation (like TB).
Typhoid Fever(salmonella) case #36
G- rod, no lactose ferment, encapsulated. Traveler. Enters terminal illeum to submucosal lymph nodes. Survives in macrophages. Maculopap lesions caused by thrombocytopenia.
H. pylori case #45
Serology. G-rod, urease+, microaerophilic, poor, elderly, no invasion, high inflammation. VacA CagA(high IL8), PMN infiltration into lamina propria.
Aseptic meningitis(HSV) case #61
PCR. MR:irregular area of hemorrhagic necrosis right temporal lobe. CSF: high WBC 82% lymphos, normal glucose, elevated protein. Trigeminal gangia latency. Direct necrosis by virus to brain parenchyma. Also perivascular necrosis->hemorrhage.
Rocky Mountain Spotted Fever case #80
Serologic response to antigens. 24 hr onset. Southeast. rOmpA protein, spread by actin polymerization. No cyto/endotoxin. Hypoproteinemia.
Bubonic plague(yersinia pestis) case #85
Nonmotile, G-, safetypin shaped, oxidase-, ferment glucose, reduce nitrates, spread to lymph and then blood. can cause interstitial pneumonic disease.
Encephalitis(West Nile) case #89
MR: increased signal in basal ganglia. CSF: 42 cells/ul, high protein, normal glucose. IgM neutralized antibody test. Culex mosquito. Hematogenous dissemination localized to CNS. Scattered microglial nodules and perivascular inflammatory infiltrates. Accute flaccid paralysis.
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