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Pharm II: Men's Health
Terms in this set (19)
Alpha 1 Antagonist MOA in respect to BPH
Relax prostatic smooth muscle by blocking alpha 1 adrenergc activity and NE inhibition
Non-selective alpha 1 antagonists in respect to BPH
Selective alpha 1 antagonist in respect to BPH
What is the first line Tx for BPH for moderate to severe Sx with an AUA score of >8?
What BPH Alpha Blocker has tiredness, asthenia, retrograde ejaculation, and nasal congestion as common side effects?
5-Alpha Reductase Inhibitors MOA in respect to hypogonadism
Converts testosterone to dihydrotestosterone
5-Alpha Reductase inhibitors in respect to Men's Health
What 5-Alpha Reductase Inhibitor is specific for type II enzyme?
What 5-Alpha Reductase Inhibitor is nonspecific for type Iand II enzyme?
What is an FDA approved medication that can treat BPH alone or BPH with erectile dysfunction?
What supplement is thought to have 5a-reductase inhibitor properties that can help with BPH?
Phosphodiesterase 5 Inhibitors MOA
Inhibit PDE-5 which is found in genital tissue, to prevent breakdown of cGMP, and enhancing the NO response --> vasodilation
What is considered first line therapy for Erectile Dysfunction tx?
Testosterone replacement for hypogonadism
PDE-5 Inhibitors in respect to ED
Blue-green color discrimination and light sensitivity due to PDE-6 inhibition can be a side effect of which medications for ED?
In respect to ED, What is the only PDE-5 I that is approved for daily use?
What medication causes an inhibition of PDE-11 in skeletal muscle that can lead to back and muscle pain?
Intraurethral Alprostadil MOA
Prostaglandin E1 induces smooth muscle relaxation and vasodilation
What medication can cause Erythrocytosis (Polycythemia) in patients taking hormone replacement?
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